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Interleukin-5 (Human, Recombinant)

$695.00 $495.00

Catalog Number: B2010312 (10 ug)
Interleukin-5 (Human, Recombinant) is a high quality research product used as highly pure Interleukin-5 (Human, Recombinant) expressed in CHO. This protein acts as a selective activator of human eosinophil function. Custom bulk orders of this product are available upon request.

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SKU: B2010312 Categories: , ,

Description

Interleukin-5 (Human, Recombinant)
Catalog number: B2010312
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 10 ug
pH: 7.4 upon reconstitution
Supplied as: Lyophilized Powder
Appearance: Powder
Applications: highly pure Interleukin-5 (Human, Recombinant) expressed in CHO. This protein acts as a selective activator of human eosinophil function.
Storage: -20C
Keywords: rHuIL-5; EDF; BCDFII; TRF
Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Bagnasco D, Ferrando M, Caminati M, Bragantini A, Puggioni F, Varricchi G,
Passalacqua G, Canonica GW. Targeting Interleukin-5 or Interleukin-5Rα: Safety
Considerations. Drug Saf. 2017 Jul;40(7):559-570.

2: Poblete MJ, Rosenbaum A, Winter M. Anti-interleukin 5 therapy for chronic
rhinosinusitis with polyps. Medwave. 2018 Oct 24;18(6):e7301. Spanish, English.

3: Takatsu K. Interleukin-5 and IL-5 receptor in health and diseases. Proc Jpn
Acad Ser B Phys Biol Sci. 2011;87(8):463-85.

4: Giannetti MP, Cardet JC. Interleukin-5 Antagonists Usher in a New Generation
of Asthma Therapy. Curr Allergy Asthma Rep. 2016 Nov;16(11):80.

5: Kay AB, Klion AD. Anti-interleukin-5 therapy for asthma and hypereosinophilic
syndrome. Immunol Allergy Clin North Am. 2004 Nov;24(4):645-66, vii.

6: Boggu PR, Kim Y, Jung SH. Discovery of benzimidazole analogs as a novel
interleukin 5 inhibitors. Eur J Med Chem. 2019 Nov 1;181:111574.

7: Corren J. Inhibition of interleukin 5 for the treatment of eosinophilic
diseases. Discov Med. 2012 Apr;13(71):305-12.

8: Roboz GJ, Rafii S. Interleukin 5 and the regulation of eosinophil production.
Curr Opin Hematol. 1999 May;6(3):164-8.

9: Karlen S, Mordvinov VA, Sanderson CJ. How is expression of the interleukin 5
gene regulated? Immunol Cell Biol. 1996 Apr;74(2):218-23.
10: Miyazaki J, Takaki S, Araki K, Tashiro F, Tominaga A, Takatsu K, Yamamura K.
Expression vector system based on the chicken beta-actin promoter directs
efficient production of interleukin-5. Gene. 1989 Jul 15;79(2):269-77.

Products Related to Interleukin-5 (Human, Recombinant) : Proteins

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