Inosine 5′-Triphosphate (Sodium Salt)


Catalog Number: B2013106 (10 mg)
Inosine 5′-Triphosphate (Sodium Salt) is a high quality nucleoside triphosphate used as an alternative substrate for ATPases and GTPases. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Inosine 5′-Triphosphate (Sodium Salt)
Catalog number: B2013106
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 mg
Molecular Weight or Concentration: 574.1 g/mol
Supplied as: Lyophilized Powder
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: inosine 5′-(tetrahydrogen triphosphate), trisodium salt
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Senthilvelan A, Shanmugasundaram M, Kore AR. An efficient protection-free chemical synthesis of inosine 5′-nucleotides Nucleosides Nucleotides Nucleic Acids. 2020;39(6):829-837.
2: Morgan MA, Shatkin AJ. Initiation of reovirus transcription by inosine 5′-triphosphate and properties of 7-methylinosine-capped, inosine-substituted messenger ribonucleic acids Biochemistry. 1980 Dec 23;19(26):5960-6.
3: Nakahara K, Hataya T, Uyeda I. Inosine 5′-triphosphate can dramatically increase the yield of NASBA products targeting GC-rich and intramolecular base-paired viroid RNA Nucleic Acids Res. 1998 Apr 1;26(7):1854-6.
4: Loukovaara S, Sahanne S, Jalkanen S, Yegutkin GG. Increased intravitreal adenosine 5′-triphosphate, adenosine 5′-diphosphate and adenosine 5′-monophosphate levels in patients with proliferative diabetic retinopathy Acta Ophthalmol. 2015 Feb;93(1):67-73.
5: Nyström K, Wanrooij PH, Waldenström J, Adamek L, Brunet S, Said J, Nilsson S, Wind-Rotolo M, Hellstrand K, Norder H, Tang KW, Lagging M. Inosine Triphosphate Pyrophosphatase Dephosphorylates Ribavirin Triphosphate and Reduced Enzymatic Activity Potentiates Mutagenesis in Hepatitis C Virus J Virol. 2018 Sep 12;92(19):e01087-18.
6: Hourani SM, Bailey SJ, Johnson CR, Tennant JP. Effects of adenosine 5′-triphosphate, uridine 5′-triphosphate, adenosine 5′-tetraphosphate and diadenosine polyphosphates in guinea-pig taenia caeci and rat colon muscularis mucosae Naunyn Schmiedebergs Arch Pharmacol. 1998 Oct;358(4):464-73.
7: Carson DA, Wasson DB. Characterization of an adenosine 5′-triphosphate- and deoxyadenosine 5′-triphosphate-activated nucleotidase from human malignant lymphocytes Cancer Res. 1982 Nov;42(11):4321-4.
8: Göttle M, Dove S, Seifert R. Bacillus anthracis edema factor substrate specificity: evidence for new modes of action Toxins (Basel). 2012 Jul;4(7):505-35.
9: Sigel H, Bianchi EM, Corfù NA, Kinjo Y, Tribolet R, Martin RB. Stabilities and isomeric equilibria in solutions of monomeric metal-ion complexes of guanosine 5′-triphosphate (GTP4-) and inosine 5′-triphosphate (ITP4-) in comparison with those of adenosine 5′-triphosphate (ATP4-) Chemistry. 2001 Sep 3;7(17):3729-37.
10: Hübner M, Dixit A, Mou TC, Lushington GH, Pinto C, Gille A, Geduhn J, König B, Sprang SR, Seifert R. Structural basis for the high-affinity inhibition of mammalian membranous adenylyl cyclase by 2′,3′-o-(N-methylanthraniloyl)-inosine 5′-triphosphate Mol Pharmacol. 2011 Jul;80(1):87-96.

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Additional information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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