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IKKβ Antibody Polyclonal

$995.00

Catalog Number: B2010553 (100 ug)
IKKβ Antibody Polyclonal is a rabbit polyclonal antibody specific to human IKKβ. This product has been used as molecular tool in various immunoapplications related to IKKβ (a member of the IKK complex that is important in NFkB regulation). It has also been used in a wide array of other biochemical applications. Custom bulk amounts of this product are available upon request.

Live enquiry about this product via Text/SMS: 1-858-900-3210.

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SKU: B2010553 Categories: ,

Description

IKKβ Antibody Polyclonal
Catalog number: B2010553
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 ug
Molecular Weight or Concentration: 150 kDa
Supplied as: Purified IgG
Applications: molecular tool in various immunoapplications related to IKKβ (a member of the IKK complex that is important in NFkB regulation)
Storage: -20C
Keywords: Anti-IKKβ Antibody
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Häcker H, Karin M. Regulation and function of IKK and IKK-related kinases.
Sci STKE. 2006 Oct 17;2006(357):re13.

2: Gu L, Zhu Y, Lin X, Lu B, Zhou X, Zhou F, Zhao Q, Prochownik EV, Li Y. The
IKKβ-USP30-ACLY Axis Controls Lipogenesis and Tumorigenesis. Hepatology. 2021
Jan;73(1):160-174.

3: Fang R, Wang C, Jiang Q, Lv M, Gao P, Yu X, Mu P, Zhang R, Bi S, Feng JM,
Jiang Z. NEMO-IKKβ Are Essential for IRF3 and NF-κB Activation in the cGAS-STING
Pathway. J Immunol. 2017 Nov 1;199(9):3222-3233.

4: Douglass JD, Dorfman MD, Fasnacht R, Shaffer LD, Thaler JP. Astrocyte
IKKβ/NF-κB signaling is required for diet-induced obesity and hypothalamic
inflammation. Mol Metab. 2017 Jan 28;6(4):366-373.

5: Zhang X, Zhang G, Zhang H, Karin M, Bai H, Cai D. Hypothalamic IKKbeta/NF-
kappaB and ER stress link overnutrition to energy imbalance and obesity. Cell.
2008 Oct 3;135(1):61-73.

6: Page A, Navarro M, Suárez-Cabrera C, Bravo A, Ramirez A. Context-Dependent
Role of IKKβ in Cancer. Genes (Basel). 2017 Dec 8;8(12):376.

7: Purkayastha S, Cai D. Neuroinflammatory basis of metabolic syndrome. Mol
Metab. 2013 Oct 5;2(4):356-63.

8: Yamada A, Kawasaki M, Miake Y, Yamada Y, Blackburn J, Kawasaki K, Trakanant
S, Nagai T, Nihara J, Kudo T, Meguro F, Schmidt-Ullrich R, Liu B, Hu Y, Page A,
Ramírez Á, Sharpe PT, Maeda T, Takagi R, Ohazama A. Overactivation of the NF-κB
pathway impairs molar enamel formation. Oral Dis. 2020 Oct;26(7):1513-1522.

9: Guo K, Chen J, Chen Z, Luo G, Yang S, Zhang M, Hong J, Zhang L, Chen C.
Triptolide alleviates radiation-induced pulmonary fibrosis via inhibiting IKKβ
stimulated LOX production. Biochem Biophys Res Commun. 2020 Jun
18;527(1):283-288.
10: Koteish A, Mae Diehl A. Animal models of steatohepatitis. Best Pract Res
Clin Gastroenterol. 2002 Oct;16(5):679-90.

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