IKKβ Antibody Polyclonal

Description

IKKβ Antibody Polyclonal
Catalog number: B2010553
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 ug
Molecular Weight or Concentration: 150 kDa
Supplied as: Purified IgG
Applications: molecular tool in various immunoapplications related to IKKβ (a member of the IKK complex that is important in NFkB regulation)
Storage: -20C
Keywords: Anti-IKKβ Antibody
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Häcker H, Karin M. Regulation and function of IKK and IKK-related kinases.
Sci STKE. 2006 Oct 17;2006(357):re13.

2: Gu L, Zhu Y, Lin X, Lu B, Zhou X, Zhou F, Zhao Q, Prochownik EV, Li Y. The
IKKβ-USP30-ACLY Axis Controls Lipogenesis and Tumorigenesis. Hepatology. 2021
Jan;73(1):160-174.

3: Fang R, Wang C, Jiang Q, Lv M, Gao P, Yu X, Mu P, Zhang R, Bi S, Feng JM,
Jiang Z. NEMO-IKKβ Are Essential for IRF3 and NF-κB Activation in the cGAS-STING
Pathway. J Immunol. 2017 Nov 1;199(9):3222-3233.

4: Douglass JD, Dorfman MD, Fasnacht R, Shaffer LD, Thaler JP. Astrocyte
IKKβ/NF-κB signaling is required for diet-induced obesity and hypothalamic
inflammation. Mol Metab. 2017 Jan 28;6(4):366-373.

5: Zhang X, Zhang G, Zhang H, Karin M, Bai H, Cai D. Hypothalamic IKKbeta/NF-
kappaB and ER stress link overnutrition to energy imbalance and obesity. Cell.
2008 Oct 3;135(1):61-73.

6: Page A, Navarro M, Suárez-Cabrera C, Bravo A, Ramirez A. Context-Dependent
Role of IKKβ in Cancer. Genes (Basel). 2017 Dec 8;8(12):376.

7: Purkayastha S, Cai D. Neuroinflammatory basis of metabolic syndrome. Mol
Metab. 2013 Oct 5;2(4):356-63.

8: Yamada A, Kawasaki M, Miake Y, Yamada Y, Blackburn J, Kawasaki K, Trakanant
S, Nagai T, Nihara J, Kudo T, Meguro F, Schmidt-Ullrich R, Liu B, Hu Y, Page A,
Ramírez Á, Sharpe PT, Maeda T, Takagi R, Ohazama A. Overactivation of the NF-κB
pathway impairs molar enamel formation. Oral Dis. 2020 Oct;26(7):1513-1522.

9: Guo K, Chen J, Chen Z, Luo G, Yang S, Zhang M, Hong J, Zhang L, Chen C.
Triptolide alleviates radiation-induced pulmonary fibrosis via inhibiting IKKβ
stimulated LOX production. Biochem Biophys Res Commun. 2020 Jun
18;527(1):283-288.
10: Koteish A, Mae Diehl A. Animal models of steatohepatitis. Best Pract Res
Clin Gastroenterol. 2002 Oct;16(5):679-90.

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