Human Thyroid Stimulating Hormone Receptor Antibody

Description

Human Thyroid Stimulating Hormone Receptor (TSHR) Monoclonal Antibody
Catalog number: B2010241
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 4 ug
pH: na
Supplied as: Ready-to-use
Appearance: Lyophilized Powder
Applications: high purity human monoclonal autoantibody to the TSH receptor. This product is suitable for many applications including assays, bioassays and immunohistochemistry.
Storage: -20C
Keywords: TSHR antibody, hTSHR antibody
Grade: Biotechnology grade. All components are highly pure (minimum 99%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered on a 0.22 um.

References:
1: Pujol-Borrell R, Álvarez-Sierra D, Jaraquemada D, Marín-Sánchez A, Colobran
R. Central Tolerance Mechanisms to TSHR in Graves’ Disease: Contributions to
Understand the Genetic Association. Horm Metab Res. 2018 Dec;50(12):863-870.

2: Zhou L, Wu K, Zhang L, Gao L, Chen S. Liver-specific deletion of TSHR
inhibits hepatic lipid accumulation in mice. Biochem Biophys Res Commun. 2018
Feb 26;497(1):39-45.

3: Liu T, Men Q, Su X, Chen W, Zou L, Li Q, Song M, Ouyang D, Chen Y, Li Z, Fu
X, Yang A. Downregulated expression of TSHR is associated with distant
metastasis in thyroid cancer. Oncol Lett. 2017 Dec;14(6):7506-7512.

4: Pujol-Borrell R, Giménez-Barcons M, Marín-Sánchez A, Colobran R. Genetics of
Graves’ Disease: Special Focus on the Role of TSHR Gene. Horm Metab Res. 2015
Sep;47(10):753-66.

5: Huth S, Jaeschke H, Schaarschmidt J, Paschke R. Controversial constitutive
TSHR activity: patients, physiology, and in vitro characterization. Horm Metab
Res. 2014 Jun;46(7):453-61.

6: Fang Y, Sun F, Zhang RJ, Zhang CR, Yan CY, Zhou Z, Zhang QY, Li L, Ying YX,
Zhao SX, Liang J, Song HD. Mutation screening of the TSHR gene in 220 Chinese
patients with congenital hypothyroidism. Clin Chim Acta. 2019 Oct;497:147-152.

7: Zhou C, Li J, Wang Y, Xue S, Zhang Y. Association of BRAF gene and TSHR with
cervical lymph node metastasis of papillary thyroid microcarcinoma. Oncol Lett.
2019 Jan;17(1):183-194.

8: Shih YL, Huang YH, Lin KH, Chu YD, Yeh CT. Identification of Functional
Thyroid Stimulating Hormone Receptor and TSHR Gene Mutations in
Hepatocellular Carcinoma. Anticancer Res. 2018 May;38(5):2793-2802.

Products Related to Human Thyroid Stimulating Hormone Receptor (TSHR) Monoclonal Antibody: Antibodies