Human SHP-1 Protein


Catalog Number: B2014225 (5 μg)
Human SHP-1 Protein is a high quality recombinant human full-length SHP-1 for use in Phosphatase Assays. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Human SHP-1 Protein
Catalog number: B2014225
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 μg
Molecular Weight or Concentration: 95 kDa
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: −20°C
Keywords: SHP-1 Protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Ma P, Foote DC, Sinnamon AJ, Brass LF. Dissociation of SHP-1 from spinophilin during platelet activation exposes an inhibitory binding site for protein phosphatase-1 (PP1) PLoS One. 2015 Mar 18;10(3):e0119496.
2: Tsubata T. Role of inhibitory BCR co-receptors in immunity Infect Disord Drug Targets. 2012 Jun;12(3):181-90.
3: He DC, Xiao JJ, Zhang Y, Lin H, Ding XJ, Tu Y. Effect of the Jianpi Bushen Prescription on the expression of SHP-1, Wnt3a, and AP-1 proteins in chemically damaged mice Genet Mol Res. 2014 Apr 25;13(2):3201-8.
4: Ahmad JN, Cerny O, Linhartova I, Masin J, Osicka R, Sebo P. cAMP signalling of Bordetella adenylate cyclase toxin through the SHP-1 phosphatase activates the BimEL-Bax pro-apoptotic cascade in phagocytes Cell Microbiol. 2016 Mar;18(3):384-98.
5: Mastrodimou N, Kiagiadaki F, Hodjarova M, Karagianni E, Thermos K. Somatostatin receptors (sst2) regulate cGMP production in rat retina Regul Pept. 2006 Jan 15;133(1-3):41-6.
6: Speranza L, Pesce M, Patruno A, Franceschelli S, Lutiis MA, Grilli A, Felaco M. Astaxanthin treatment reduced oxidative induced pro-inflammatory cytokines secretion in U937: SHP-1 as a novel biological target Mar Drugs. 2012 Apr;10(4):890-899.
7: Munz M, Willenborg C, Richter GM, Jockel-Schneider Y, Graetz C, Staufenbiel I, Wellmann J, Berger K, Krone B, Hoffmann P, van der Velde N, Uitterlinden AG, de Groot LCPGM, Sawalha AH, Direskeneli H, Saruhan-Direskeneli G, Guzeldemir-Akcakanat E, Keceli HG, Laudes M, Noack B, Teumer A, Holtfreter B, Kocher T, Eickholz P, Meyle J, Doerfer C, Bruckmann C, Lieb W, Franke A, Schreiber S, Nohutcu RM, Erdmann J, Loos BG, Jepsen S, Dommisch H, Schaefer AS. A genome-wide association study identifies nucleotide variants at SIGLEC5 and DEFA1A3 as risk loci for periodontitis Hum Mol Genet. 2017 Jul 1;26(13):2577-2588.
8: Fang JC, Su ZL, Qiu G, He D, Feng ZY, Zhu MF, Li L, He XL. [SHP-1 gene’s methylation status of Daudi lymphoma cell and the demethylation effect of 5-aza-2′-deoxycytidine] Zhonghua Xue Ye Xue Za Zhi. 2006 Oct;27(10):670-4.
9: He DC, Xiao JJ, Zhang Y, Lin H, Ding XJ, Tu Y. Effect of Jianpi Bushen prescription on the expression of SHP-1 and apoptosis-related genes in chemically damaged model mice Genet Mol Res. 2014 Aug 7;13(3):5957-63.
10: Oomen SP, Ward AC, Hofland LJ, Lamberts SW, Lwenberg B, Touw IP. Somatostatin modulates G-CSF-induced but not interleukin-3-induced proliferative responses in myeloid 32D cells via activation of somatostatin receptor subtype 2 Hematol J. 2001;2(5):322-9.

Products Related to Human SHP-1 Protein can be found at Proteins

Additional information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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