Human Recombinant Glypican 5 Protein


Catalog Number: B2012595 (100 ug)
Human Recombinant Glypican 5 Protein is a high quality cell membrane protein that belongs to the glypican family and play a role in the control of cell division and growth regulation. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Human Recombinant Glypican 5 Protein
Catalog number: B2012595
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 ug
Molecular Weight or Concentration: N/A
Supplied as: Lyophilized Powder
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: GPC5
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Svensson G, Linse S, Mani K. Chemical and thermal unfolding of glypican-1: protective effect of heparan sulfate against heat-induced irreversible aggregation Biochemistry. 2009 Oct 27;48(42):9994-10004.
2: Buhl JP, Garten A, Kratzsch J, Kiess W, Penke M. How Reliable are Commercially Available Glypican4 ELISA Kits? Exp Clin Endocrinol Diabetes. 2022 Feb;130(2):110-114.
3: Svensson G, Hyrenius Wittsten A, Linse S, Mani K. The structural role of N-linked glycans on human glypican-1 Biochemistry. 2011 Nov 1;50(43):9377-87.
4: Wang S, Kalim M, Liang K, Zhan J. Polyclonal antibody production against rGPC3 and their application in diagnosis of hepatocellular carcinoma Prep Biochem Biotechnol. 2018 May 28;48(5):435-445.
5: Li Y, Siegel DL, Scholler N, Kaplan DE. Validation of glypican-3-specific scFv isolated from paired display/secretory yeast display library BMC Biotechnol. 2012 May 7;12:23.
6: Fleming BD, Ho M. Development of Glypican-3 Targeting Immunotoxins for the Treatment of Liver Cancer: An Update Biomolecules. 2020 Jun 20;10(6):934.
7: Amor DJ, Stephenson SEM, Mustapha M, Mensah MA, Ockeloen CW, Lee WS, Tankard RM, Phelan DG, Shinawi M, de Brouwer APM, Pfundt R, Dowling C, Toler TL, Sutton VR, Agolini E, Rinelli M, Capolino R, Martinelli D, Zampino G, Dumić M, Reardon W, Shaw-Smith C, Leventer RJ, Delatycki MB, Kleefstra T, Mundlos S, Mortier G, Bahlo M, Allen NJ, Lockhart PJ. Pathogenic Variants in GPC4 Cause Keipert Syndrome Am J Hum Genet. 2019 May 2;104(5):914-924.
8: Song HH, Shi W, Filmus J. OCI-5/rat glypican-3 binds to fibroblast growth factor-2 but not to insulin-like growth factor-2 J Biol Chem. 1997 Mar 21;272(12):7574-7.
9: Matsuda K, Maruyama H, Guo F, Kleeff J, Itakura J, Matsumoto Y, Lander AD, Korc M. Glypican-1 is overexpressed in human breast cancer and modulates the mitogenic effects of multiple heparin-binding growth factors in breast cancer cells Cancer Res. 2001 Jul 15;61(14):5562-9.
10: Cheng F, Fransson LÅ, Mani K. The cyanobacterial neurotoxin β-N-methylamino-l-alanine prevents addition of heparan sulfate to glypican-1 and increases processing of amyloid precursor protein in dividing neuronal cells Exp Cell Res. 2019 Jun 15;379(2):172-181.

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