Human Prothrombin Complex


Catalog Number: B2012314 (50 IU)
Human Prothrombin Complex is a high quality Human Prothrombin Complex. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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SKU: B2012314 Categories: , Tag:


Human Prothrombin Complex
Catalog number: B2012314
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 IU
Molecular Weight or Concentration: NA
Supplied as: Lyophilized
Applications: molecular tool for various biochemical applications
Storage: -20C
Keywords: PCC
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Nederpelt CJ, Naar L, Krijnen P, le Cessie S, Kaafarani HMA, Huisman MV, Velmahos GC, Schipper IB. Andexanet Alfa or Prothrombin Complex Concentrate for Factor Xa Inhibitor Reversal in Acute Major Bleeding: A Systematic Review and Meta-Analysis Crit Care Med. 2021 Oct 1;49(10):e1025-e1036.
2: N Engl J Med. 1965 Sep 23;273(13):715-6. doi: 10.1056/NEJM196509232731311. Human prothrombin complex N Engl J Med
3: Schwebach AA, Waybright RA, Johnson TJ. Fixed-Dose Four-Factor Prothrombin Complex Concentrate for Vitamin K Antagonist Reversal: Does One Dose Fit All? Pharmacotherapy. 2019 May;39(5):599-608.
4: Stevens VM, Trujillo TC, Kiser TH, MacLaren R, Reynolds PM, Mueller SW. Retrospective Comparison of Andexanet Alfa and 4-Factor Prothrombin Complex for Reversal of Factor Xa-Inhibitor Related Bleeding Clin Appl Thromb Hemost. 2021 Jan-Dec;27:10760296211039020.
5: Bertolaccini ML. Antibodies to prothrombin Lupus. 2012 Jun;21(7):729-31.
6: Kamihara Y, Kikuchi S, Wada A, Murakami J, Sugie N, Niimi H, Nakashima A, Sato T. [Successful preoperative replacement of prothrombin with prothrombin complex concentrate for Prothrombin Himi] Rinsho Ketsueki. 2021;62(9):1412-1414.
7: Green D. Pathophysiology of Antiphospholipid Syndrome Thromb Haemost. 2022 Jul;122(7):1085-1095.
8: DeWitt RT, Feinstein DI. Prothrombin complex concentrate Arch Intern Med. 1977 Sep;137(9):1211-3.
9: Eltringham-Smith LJ, Yu R, Qadri SM, Wang Y, Bhakta V, Pryzdial EL, Crosby JR, Ni H, Sheffield WP. Prothrombin, alone or in complex concentrates or plasma, reduces bleeding in a mouse model of blood exchange-induced coagulopathy Thromb Haemost. 1991 Dec 2;66(6):629-32.
10: Bevers EM, Galli M, Barbui T, Comfurius P, Zwaal RF. Lupus anticoagulant IgG’s (LA) are not directed to phospholipids only, but to a complex of lipid-bound human prothrombin Thromb Haemost. 1991 Dec 2;66(6):629-32.

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