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Human Normal Microglia Tissue cDNA

Original price was: $1,595.00.Current price is: $795.00.

Catalog Number: B2027163 (50 ug)
This product consists of high-purity complementary DNA (cDNA) produced from the total RNA of normal, healthy human microglia tissue. It serves as a reliable, pre-prepared genetic template for evaluating physiological gene expression profiles, regulatory pathways, and homeostatic markers in the central nervous system without the logistical challenges of fresh tissue isolation. The cDNA is optimized for immediate use in downstream molecular applications such as quantitative PCR (qPCR), gene cloning, and microfluidic expression profiling. Custom bulk amounts of this product are available upon request.

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Product Description

5/5 - (1 vote)

Human Normal Microglia Tissue cDNA
Catalog number: B2027163
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 ug
Molecular Weight or Concentration: NA
Supplied as: Solution
Storage: −20°C
Keywords: Human Normal Microglia Tissue complementary DNA

References:
1. van der Poel M, Ulas T, Mizee MR, et al. Transcriptional profiling of human microglia reveals grey-white matter heterogeneity and early activation in multiple sclerosis. Nature Neuroscience. 2019;22(8):1300-1309.
2. Bennett ML, Bennett FC, Liddelow SA, et al. New tools for studying microglia in the mouse and human CNS. Proceedings of the National Academy of Sciences. 2016;113(12):E1738-E1746.
3. Mizee MR, Woering MI, van der Poel M, et al. Isolation and characterization of human microglia from post-mortem brain tissue. Glia. 2017;65(1):154-167.
4. Galatro TF, Holtman IR, Lerario AM, et al. Transcriptomic analysis of purified human cortical microglia reveals age-associated changes. Nature Neuroscience. 2017;20(8):1162-1171.
5. Olah M, Patrick E, Villani AC, et al. A transcriptomic atlas of aged human microglia. Nature Communications. 2018;9(1):539.
6. Srinivasan K, Friedman BA, Larson JL, et al. Untangling the brain’s neuroinflammatory responses using transcriptomics. Nature Communications. 2020;11(1):4321.
7. Sankowski R, Monaco S, Bresesti C, et al. Mapping microglia states in the human brain through the integration of bulk and single-cell RNA-sequencing. Nature Neuroscience. 2019;22(12):2098-2110.
8. Masuda T, Sankowski R, Staszewski O, et al. Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution. Nature. 2019;566(7744):388-392.
9. Gosselin D, Skola D, Coufal NG, et al. An epigenetic alignment of microglia with their microenvironment in the human brain. Science. 2017;356(6344):eaal3222.
10. Thion MS, Low D, Silvin A, et al. Microbiome influences prenatal and adult microglia in a sex-specific manner. Cell. 2018;172(4):700-716.
Human Normal Microglia Tissue cDNA

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Additional Information

Weight 0.15 oz
Dimensions 2 × 0.5 × 0.5 in
5/5 - (1 vote)

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