Human Medium Oxidized Low Density Lipoprotein

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Human Medium Oxidized Low Density Lipoprotein
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Human Medium Oxidized Low Density Lipoprotein

Original price was: $1,595.00.Current price is: $795.00.

Catalog Number: B2027100 (1 mg)
Human Medium Oxidized Low Density Lipoprotein (Ox-LDL) is a modified form of LDL prepared through the controlled chemical oxidation of lipid and protein components, including apolipoprotein B-100, by reactive oxygen species. This structurally distinct lipoprotein features oxidized phospholipids and altered apolipoprotein B structures, resulting in enhanced negative charge and specific binding to macrophage scavenger receptors like CD36 and SR-A. Custom bulk amounts of this product are available upon request.

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Product Description

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Human Medium Oxidized Low Density Lipoprotein
Catalog number: B2027100
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: NA
Supplied as: Solution
Storage: 2-8°C
Keywords: Medium Oxidized LDL, oxLDL, low density lipoprotein, human protein, lipid research, cellular uptake, scavenger receptor, foam cell formation, endocytosis

References:
1. Holvoet P, Vanhaecke J, Janssens S, Van de Werf F, Collen D. (1998). Oxidized LDL and malondialdehyde-modified LDL in patients with acute coronary syndromes and stable coronary artery disease. Circulation, 98(15), 1487-94.
2. Holvoet P, Kritchevsky SB, Tracy RP, Mertens A, Rubin SM, Butler J, Goodpaster B, Harris TB. (2008). Association between circulating oxidized low-density lipoprotein and incidence of the metabolic syndrome. JAMA, 299(19), 2287-93.
3. Nishi K, Itabe H, Uno M, Kitazato KT, Imamura H, Yamamoto K, Sato K, Nagahiro S. (2002). Oxidized LDL in carotid plaques and plasma associates with plaque instability. Arteriosclerosis, Thrombosis, and Vascular Biology, 22(10), 1649-54.
4. Meisinger C, Baumert J, Khuseyinova N, Loewel H, Koenig W. (2005). Plasma oxidized low-density lipoprotein, a strong predictor for acute coronary heart disease events in apparently healthy, middle-aged men from the general population. Circulation, 112(5), 651-7.
5. Steinberg D, Parthasarathy S, Carew TE, Khoo JC, Witztum JL. (1989). Modifications of low-density lipoprotein that increase its atherogenicity. The New England Journal of Medicine, 320(14), 915-24.
6. Witztum JL, Steinberg D. (1991). Role of oxidized low density lipoprotein in atherogenesis. Journal of Clinical Investigation, 88(6), 1785-92.
7. Itabe H, Obama T, Kato R. (2011). The building blocks of oxidized LDL: An overview of the generation and chemical nature of oxidized low-density lipoprotein. Clinica Chimica Acta, 412(21-22), 1890-7.
8. Berliner JA, Navab M, Fogelman AM, Frank JS, Demer LL, Edwards PA, Watson AD, Lusis AJ. (1995). Atherosclerosis: basic mechanisms: oxidation, inflammation, and genetics. Circulation, 91(9), 2488-96.
9. Parthasarathy S, Raghavamenon A, Garelnabi MO, Santanam N. (2010). Oxidized low-density lipoprotein. Methods in Molecular Biology, 610, 403-17.
10. Sorokin AV, Florida E, Li H, Parel PM, Mehta NN, Hong CG. (2024). Oxidized low-density lipoprotein associates with cardiovascular disease by a vicious cycle of atherosclerosis and inflammation: A systematic review and meta-analysis. Journal of Clinical Lipidology, 18(3), e345-e356.
Human Medium Oxidized Low Density Lipoprotein

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Additional Information

Weight 0.15 oz
Dimensions 2 × 0.5 × 0.5 in
5/5 - (1 vote)

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