Human MARK1 Active

Description

Human MARK1 Active
Catalog number: B2014344
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 μg
Molecular Weight or Concentration: ~125 kDa
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: KIAA1477
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Dong Y, Zhao Q, Wang Y. Network pharmacology-based investigation of potential targets of astragalus membranaceous-angelica sinensis compound acting on diabetic nephropathy Sci Rep. 2021 Sep 30;11(1):19496.
2: Ghosh DK, Ranjan A. HYPK coordinates degradation of polyneddylated proteins by autophagy Autophagy. 2022 Aug;18(8):1763-1784.
3: Fumoto K, Takigawa-Imamura H, Sumiyama K, Yoshimura SH, Maehara N, Kikuchi A. Mark1 regulates distal airspace expansion through type I pneumocyte flattening in lung development J Cell Sci. 2019 Dec 13;132(24):jcs235556.
4: Molina E, Hong L, Chefetz I. AMPK-like proteins as LKB1 downstream targets in cell physiology and cancer J Mol Med (Berl). 2021 May;99(5):651-662.
5: Jeon S, Kim YS, Park J, Bae CD. Microtubule affinity-regulating kinase 1 (MARK1) is activated by electroconvulsive shock in the rat hippocampus J Neurochem. 2005 Dec;95(6):1608-18.
6: Emptage RP, Lemmon MA, Ferguson KM. Molecular determinants of KA1 domain-mediated autoinhibition and phospholipid activation of MARK1 kinase Biochem J. 2017 Feb 1;474(3):385-398.
7: Chen Z, Huang M, You J, Lin Y, Huang Q, He C. Circular RNA hsa_circ_0023404 promotes the proliferation, migration and invasion in endometrial cancer cells through regulating miR-217/MAPK1 axis Eur J Med Res. 2022 Nov 9;27(1):242.
8: Emptage RP, Lemmon MA, Ferguson KM, Marmorstein R. Structural Basis for MARK1 Kinase Autoinhibition by Its KA1 Domain Structure. 2018 Aug 7;26(8):1137-1143.e3.
9: Wu PR, Tsai PI, Chen GC, Chou HJ, Huang YP, Chen YH, Lin MY, Kimchi A, Chien CT, Chen RH. DAPK activates MARK1/2 to regulate microtubule assembly, neuronal differentiation, and tau toxicity Cell Death Differ. 2011 Sep;18(9):1507-20.
10: Zheng X, Xu K, Zhu L, Mao M, Zhang F, Cui L. MiR-486-5p Act as a Biomarker in Endometrial Carcinoma: Promotes Cell Proliferation, Migration, Invasion by Targeting MARK1 Onco Targets Ther. 2020 May 28;13:4843-4853.

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