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Human Leukocytes

Original price was: $1,595.00.Current price is: $795.00.

Catalog Number: B2027162 (1 mL)
Human Leukocyte Antigens (HLA) are highly polymorphic cell-surface glycoproteins encoded by the Major Histocompatibility Complex (MHC) on chromosome 6. These molecules play a role in immune regulation by binding and presenting intracellular or extracellular peptide antigens to T lymphocytes to differentiate self from non-self. Custom bulk amounts of this product are available upon request.

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SKU: B2027162 Category: Tag:

Product Description

5/5 - (3 votes)

Human Leukocytes
Catalog number: B2027162
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mL
Molecular Weight or Concentration: NA
Supplied as: Solution
Storage: RT
Keywords: HLA, Human Leukocyte Antigen, MHC, Major Histocompatibility Complex

References:
1. Muro M, Legaz I. Importance of human leukocyte antigen antibodies and leukocyte antigen/killer-cell immunoglobulin-like receptor genes in liver transplantation. World Journal of Gastroenterology. 2023;29(5):766-772.
2. Rozengurt J. Human Leukocyte Antigens and the Immune System’s role in Self-Recognition. Immunogenetics: Open Access. 2024;9:241.
3. Zhu L, et al. Non-classical human leukocyte antigens in solid cancers: Roles in tumor immune escape and potential as therapeutic targets. Frontiers in Immunology. 2024.
4. Brunner D, et al. Human leukocyte antigen (HLA) Class I and II alleles and their broad protective or susceptibility effects across multiple cancer types. International Journal of Oncology. 2024.
5. Lee DY, Lee SY, Park YH. The role of classical and non-classical HLA alleles in immune regulation and viral pathogenesis of HIV and HCV. Trends in Biotechnology. 2022;40(8):950-965.
6. Altschuler SJ, Wu LF. Cellular heterogeneity and the complex role of HLA-B*35 subtypes in HIV-1 disease progression. Cell. 2010;141(4):559-563.
7. Hoang DM, et al. Association between HLA-G gene polymorphisms and susceptibility to Sjögren’s syndrome in a Saudi population. Stem Cell Research & Therapy. 2022.
8. Zhang Y, et al. HLA-E surface expression and its clinical significance in serous ovarian carcinoma and non-small cell lung cancer. Journal of Dermatological Science. 2023.
9. Havel RJ, Eder HA, Bragdon JH. Inherited disease tendencies and haplotype transmission within the HLA class II region. Journal of Clinical Investigation. 1955;34(9):1345-1353.
10. Subbiahanadar Chelladurai K, Selvanasan S, Rajagopalan K, et al. The evolutionary history of HLA typing technologies: From serological methods to third-generation sequencing. Journal of Bioscience and Bioengineering. 2021;131(5):455-463.
Human Leukocyte

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Additional Information

Weight 0.15 oz
Dimensions 2 × 0.5 × 0.5 in
5/5 - (3 votes)

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