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Glial Cell Line-derived Neurotrophic Factor

$495.00

Catalog Number: B2010363 (10 ug)
Human Glial Cell Line-derived Neurotrophic Factor is a high quality research product used as highly pure Human Glial Cell Line-derived Neurotrophic Factor expressed in E. coli. This protein acts as a small protein that potently promotes the survival of many types of neurons. Custom bulk orders of this product are available upon request.

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SKU: B2010363 Categories: , ,

Description

Human Glial Cell Line-derived Neurotrophic Factor
Catalog number: B2010363
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 10 ug
pH: 7.4 upon reconstitution
Supplied as: Lyophilized Powder
Appearance: Powder
Applications: highly pure Human Glial Cell Line-derived Neurotrophic Factor expressed in E. coli. This protein acts as a small protein that potently promotes the survival of many types of neurons.
Storage: -20C
Keywords: rHuGDNF; ATF
Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Chang HM, Wu HC, Sun ZG, Lian F, Leung PCK. Neurotrophins and glial cell
line-derived neurotrophic factor in the ovary: physiological and
pathophysiological implications. Hum Reprod Update. 2019 Mar 1;25(2):224-242.

2: Ayanlaja AA, Zhang B, Ji G, Gao Y, Wang J, Kanwore K, Gao D. The reversible
effects of glial cell line-derived neurotrophic factor (GDNF) in the human
brain. Semin Cancer Biol. 2018 Dec;53:212-222.

3: Whone A, Luz M, Boca M, Woolley M, Mooney L, Dharia S, Broadfoot J, Cronin D,
Schroers C, Barua NU, Longpre L, Barclay CL, Boiko C, Johnson GA, Fibiger HC,
Harrison R, Lewis O, Pritchard G, Howell M, Irving C, Johnson D, Kinch S,
Marshall C, Lawrence AD, Blinder S, Sossi V, Stoessl AJ, Skinner P, Mohr E, Gill
SS. Randomized trial of intermittent intraputamenal glial cell line-derived
neurotrophic factor in Parkinson’s disease. Brain. 2019 Mar 1;142(3):512-525.

4: Zhu S, Li Y, Bennett S, Chen J, Weng IZ, Huang L, Xu H, Xu J. The role of
glial cell line-derived neurotrophic factor family member artemin in
neurological disorders and cancers. Cell Prolif. 2020 Jul;53(7):e12860.

5: Yamada J, Akeda K, Sano T, Iwasaki T, Takegami N, Sudo A. Expression of Glial
Cell Line-derived Neurotrophic Factor in the Human Intervertebral Disc. Spine
(Phila Pa 1976). 2020 Jul 1;45(13):E768-E775.

6: Rosich K, Hanna BF, Ibrahim RK, Hellenbrand DJ, Hanna A. The Effects of Glial
Cell Line-Derived Neurotrophic Factor after Spinal Cord Injury. J Neurotrauma.
2017 Dec 15;34(24):3311-3325.

7: Tsybko AS, Ilchibaeva TV, Popova NK. Role of glial cell line-derived
neurotrophic factor in the pathogenesis and treatment of mood disorders. Rev
Neurosci. 2017 Apr 1;28(3):219-233.

8: Sidorova YA, Saarma M. Small Molecules and Peptides Targeting Glial Cell
Line-Derived Neurotrophic Factor Receptors for the Treatment of
Neurodegeneration. Int J Mol Sci. 2020 Sep 8;21(18):6575.

9: Chen M, Ba H, Lu C, Dai J, Sun J. Glial Cell Line-Derived Neurotrophic Factor
(GDNF) Promotes Angiogenesis through the Demethylation of the Fibromodulin
(FMOD) Promoter in Glioblastoma. Med Sci Monit. 2018 Sep 3;24:6137-6143.
10: Duan X, Zhu T, Chen C, Zhang G, Zhang J, Wang L, Zhang L, Wang M, Wang X.
Serum glial cell line-derived neurotrophic factor levels and postoperative
cognitive dysfunction after surgery for rheumatic heart disease. J Thorac
Cardiovasc Surg. 2018 Mar;155(3):958-965.e1.

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