Human FYN A Protein Active

Description

Human FYN A Protein Active
Catalog number: B2013828
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 ug
Molecular Weight or Concentration: 85 kDa
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: −20°C
Keywords: FYN A, active, GST tagged human
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
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2: Liao S, Wu J, Liu R, Wang S, Luo J, Yang Y, Qin Y, Li T, Zheng X, Song J, Zhao X, Xiao C, Zhang Y, Bian L, Jia P, Bai Y, Zheng X. A novel compound DBZ ameliorates neuroinflammation in LPS-stimulated microglia and ischemic stroke rats: Role of Akt(Ser473)/GSK3_(Ser9)-mediated Nrf2 activation Redox Biol. 2020 Sep;36:101644.
3: Uddin MJ, Dorotea D, Pak ES, Ha H. Fyn Kinase: A Potential Therapeutic Target in Acute Kidney Injury Biomol Ther (Seoul). 2020 May 1;28(3):213-221.
4: Beneduce E, Matte A, De Falco L, Mbiandjeu S, Chiabrando D, Tolosano E, Federti E, Petrillo S, Mohandas N, Siciliano A, Babu W, Menon V, Ghaffari S, Iolascon A, De Franceschi L. Fyn kinase is a novel modulator of erythropoietin signaling and stress erythropoiesis Am J Hematol. 2019 Jan;94(1):10-20.
5: Sayeski PP, Ali MS, Safavi A, Lyles M, Kim SO, Frank SJ, Bernstein KE. A catalytically active Jak2 is required for the angiotensin II-dependent activation of Fyn J Biol Chem. 1999 Nov 12;274(46):33131-42.
6: Banu K, Lin Q, Basgen JM, Planoutene M, Wei C, Reghuvaran AC, Tian X, Shi H, Garzon F, Garzia A, Chun N, Cumpelik A, Santeusanio AD, Zhang W, Das B, Salem F, Li L, Ishibe S, Cantley LG, Kaufman L, Lemley KV, Ni Z, He JC, Murphy B, Menon MC. AMPK mediates regulation of glomerular volume and podocyte survival JCI Insight. 2021 Oct 8;6(19):e150004.
7: Tse MC, Liu X, Yang S, Ye K, Chan CB. Fyn regulates adipogenesis by promoting PIKE-A/STAT5a interaction Mol Cell Biol. 2013 May;33(9):1797-808.
8: Zhang S, Qi Q, Chan CB, Zhou W, Chen J, Luo HR, Appin C, Brat DJ, Ye K. Fyn-phosphorylated PIKE-A binds and inhibits AMPK signaling, blocking its tumor suppressive activity Cell Death Differ. 2016 Jan;23(1):52-63.
9: Mukherjee A, Singh R, Udayan S, Biswas S, Reddy PP, Manmadhan S, George G, Kumar S, Das R, Rao BM, Gulyani A. A Fyn biosensor reveals pulsatile, spatially localized kinase activity and signaling crosstalk in live mammalian cells Elife. 2020 Feb 4;9:e50571.
10: Saminathan H, Ghosh A, Zhang D, Song C, Jin H, Anantharam V, Kanthasamy A, Kanthasamy AG. Fyn Kinase-Mediated PKC Y311 Phosphorylation Induces Dopaminergic Degeneration in Cell Culture and Animal Models: Implications for the Identification of a New Pharmacological Target for Parkinson’s Disease Front Pharmacol. 2021 Apr 28;12:631375.

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