Human CST5 Protein

Description

Human CST5 Protein
Catalog number: B2012058
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 µg
Molecular Weight or Concentration: 500 µg/mL
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: Human CST5 protein, Recombinant CST5 protein, Cystatin D protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Dyhrfort P, Shen Q, Clausen F, Thulin M, Enblad P, Kamali-Moghaddam M, Lewén A, Hillered L. Monitoring of Protein Biomarkers of Inflammation in Human Traumatic Brain Injury Using Microdialysis and Proximity Extension Assay Technology in Neurointensive Care J Neurotrauma. 2019 Oct 15;36(20):2872-2885.
2: Dickinson DP, Thiesse M, Hicks MJ. Expression of type 2 cystatin genes CST1-CST5 in adult human tissues and the developing submandibular gland DNA Cell Biol. 2002 Jan;21(1):47-65.
3: Alvarez-Díaz S, Valle N, García JM, Peña C, Freije JM, Quesada V, Astudillo A, Bonilla F, López-Otín C, Muñoz A. Cystatin D is a candidate tumor suppressor gene induced by vitamin D in human colon cancer cells J Clin Invest. 2009 Aug;119(8):2343-58.
4: Hünten S, Hermeking H. p53 directly activates cystatin D/CST5 to mediate mesenchymal-epithelial transition: a possible link to tumor suppression by vitamin D3 Oncotarget. 2015 Jun 30;6(18):15842-56.
5: Dickinson DP. Salivary (SD-type) cystatins: over one billion years in the making–but to what purpose? Crit Rev Oral Biol Med. 2002;13(6):485-508.
6: Hill LJ, Di Pietro V, Hazeldine J, Davies D, Toman E, Logan A, Belli A. Cystatin D (CST5): An ultra-early inflammatory biomarker of traumatic brain injury Sci Rep. 2017 Jul 10;7(1):5002.
7: Hatziagelaki E, Pergialiotis V, Kannenberg JM, Trakakis E, Tsiavou A, Markgraf DF, Carstensen-Kirberg M, Pacini G, Roden M, Dimitriadis G, Herder C. Association between Biomarkers of Low-grade Inflammation and Sex Hormones in Women with Polycystic Ovary Syndrome Exp Clin Endocrinol Diabetes. 2020 Nov;128(11):723-730.
8: Panezai J, Ali A, Ghaffar A, Benchimol D, Altamash M, Klinge B, Engström PE, Larsson A. Upregulation of circulating inflammatory biomarkers under the influence of periodontal disease in rheumatoid arthritis patients Cytokine. 2020 Jul;131:155117.
9: Freije JP, Balbín M, Abrahamson M, Velasco G, Dalbøge H, Grubb A, López-Otín C. Human cystatin D. cDNA cloning, characterization of the Escherichia coli expressed inhibitor, and identification of the native protein in saliva J Biol Chem. 1993 Jul 25;268(21):15737-44.
10: Saitoh E, Isemura S, Sanada K, Ohnishi K. Characterization of two members (CST4 and CST5) of the cystatin gene family and molecular evolution of cystatin genes Agents Actions Suppl. 1992;38 ( Pt 1):340-8.

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