Human CRYGS Protein

Description

Human CRYGS Protein
Catalog number: B2012040
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 µg
Molecular Weight or Concentration: 1 mg/mL
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: CRYG8 protein, Beta-crystallin S protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Forsythe HM, Vetter CJ, Jara KA, Reardon PN, David LL, Barbar EJ, Lampi KJ. Altered Protein Dynamics and Increased Aggregation of Human γS-Crystallin Due to Cataract-Associated Deamidations Biochemistry. 2019 Oct 8;58(40):4112-4124.
2: He Y, Kang J, Song J. ATP antagonizes the crowding-induced destabilization of the human eye-lens protein γS-crystallin Biochem Biophys Res Commun. 2020 Jun 11;526(4):1112-1117.
3: Wistow G, Sardarian L, Gan W, Wyatt MK. The human gene for gammaS-crystallin: alternative transcripts and expressed sequences from the first intron Mol Vis. 2000 May 17;6:79-84.
4: Ma Z, Piszczek G, Wingfield PT, Sergeev YV, Hejtmancik JF. The G18V CRYGS mutation associated with human cataracts increases gammaS-crystallin sensitivity to thermal and chemical stress Biochemistry. 2009 Aug 4;48(30):7334-41.
5: Weatherbee BAT, Barton JR, Siddam AD, Anand D, Lachke SA. Molecular characterization of the human lens epithelium-derived cell line SRA01/04 Exp Eye Res. 2019 Nov;188:107787.
6: Pande A, Mokhor N, Pande J. Deamidation of Human γS-Crystallin Increases Attractive Protein Interactions: Implications for Cataract Biochemistry. 2015 Aug 11;54(31):4890-9.
7: Wang KJ, Zhu SQ, Cheng J. [Progress in pathogenic genes and their functions of congenital cataract] Zhonghua Yan Ke Za Zhi. 2010 Mar;46(3):280-4.
8: Roskamp KW, Azim S, Kassier G, Norton-Baker B, Sprague-Piercy MA, Miller RJD, Martin RW. Human γS-Crystallin-Copper Binding Helps Buffer against Aggregation Caused by Oxidative Damage Biochemistry. 2020 Jun 30;59(25):2371-2385.
9: Karri S, Kasetti RB, Vendra VP, Chandani S, Balasubramanian D. Structural analysis of the mutant protein D26G of human γS-crystallin, associated with Coppock cataract Mol Vis. 2013 Jun 5;19:1231-7. Print 2013.
10: Huang KY, Kingsley CN, Sheil R, Cheng CY, Bierma JC, Roskamp KW, Khago D, Martin RW, Han S. Stability of Protein-Specific Hydration Shell on Crowding J Am Chem Soc. 2016 Apr 27;138(16):5392-402.

Products Related to Human CRYGS Protein can be found at Proteins