Human CHMP1B Protein

Product Description

Human CHMP1B Protein
Catalog number: B2011940
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 20 µg
Molecular Weight or Concentration: 24.7 kDa
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: CHMPB-1 protein, CHMPB 1 protein, Vps46B protein, Vps46-2 protein, C10orf2 protein, hVps46-2 protein, CHMPB-1, CHMP1B, CHMPB 1, CHMP1.5 protein, C18-ORF2 protein, C18orf2 protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Chang CL, Weigel AV, Ioannou MS, Pasolli HA, Xu CS, Peale DR, Shtengel G, Freeman M, Hess HF, Blackstone C, Lippincott-Schwartz J. Spastin tethers lipid droplets to peroxisomes and directs fatty acid trafficking through ESCRT-III J Cell Biol. 2019 Aug 5;218(8):2583-2599.
2: Nguyen HC, Talledge N, McCullough J, Sharma A, Moss FR 3rd, Iwasa JH, Vershinin MD, Sundquist WI, Frost A. Membrane constriction and thinning by sequential ESCRT-III polymerization Nat Struct Mol Biol. 2020 Apr;27(4):392-399.
3: Reid E, Connell J, Edwards TL, Duley S, Brown SE, Sanderson CM. The hereditary spastic paraplegia protein spastin interacts with the ESCRT-III complex-associated endosomal protein CHMP1B Hum Mol Genet. 2005 Jan 1;14(1):19-38.
4: Yang D, Rismanchi N, Renvoisé B, Lippincott-Schwartz J, Blackstone C, Hurley JH. Structural basis for midbody targeting of spastin by the ESCRT-III protein CHMP1B Nat Struct Mol Biol. 2008 Dec;15(12):1278-86.
5: Sewduth RN, Pandolfi S, Steklov M, Sheryazdanova A, Zhao P, Criem N, Baietti MF, Lechat B, Quarck R, Impens F, Sablina AA. The Noonan Syndrome Gene Lztr1 Controls Cardiovascular Function by Regulating Vesicular Trafficking Circ Res. 2020 May 8;126(10):1379-1393.
6: Crespo-Yàñez X, Aguilar-Gurrieri C, Jacomin AC, Journet A, Mortier M, Taillebourg E, Soleilhac E, Weissenhorn W, Fauvarque MO. CHMP1B is a target of USP8/UBPY regulated by ubiquitin during endocytosis PLoS Genet. 2018 Jun 22;14(6):e1007456.
7: Roche JV, Nesverova V, Olsson C, Deen PM, Törnroth-Horsefield S. Structural Insights into AQP2 Targeting to Multivesicular Bodies Int J Mol Sci. 2019 Oct 28;20(21):5351.
8: Scott A, Gaspar J, Stuchell-Brereton MD, Alam SL, Skalicky JJ, Sundquist WI. Structure and ESCRT-III protein interactions of the MIT domain of human VPS4A Proc Natl Acad Sci U S A. 2005 Sep 27;102(39):13813-8.
9: Skalicky JJ, Arii J, Wenzel DM, Stubblefield WM, Katsuyama A, Uter NT, Bajorek M, Myszka DG, Sundquist WI. Interactions of the human LIP5 regulatory protein with endosomal sorting complexes required for transport J Biol Chem. 2012 Dec 21;287(52):43910-26.
10: Cada AK, Pavlin MR, Castillo JP, Tong AB, Larsen KP, Ren X, Yokom AL, Tsai FC, Shiah JV, Bassereau PM, Bustamante CJ, Hurley JH. Friction-driven membrane scission by the human ESCRT-III proteins CHMP1B and IST1 Proc Natl Acad Sci U S A. 2022 Jul 19;119(29):e2204536119.

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