Human CHI3L1 Protein

Description

Human CHI3L1 Protein
Catalog number: B2011938
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 µg
Molecular Weight or Concentration: 250 µg/mL
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: GP39 protein, CHIL1 3, CHIL1-3, CHIL1-3 protein, CHIL1 3 protein, ASRT7 protein, HCGP-3P protein, YKL40 protein, YYL-40 protein, Chitinase 3-like 1 protein, CHI3L1, HC-gp39 protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Zhao T, Su Z, Li Y, Zhang X, You Q. Chitinase-3 like-protein-1 function and its role in diseases Signal Transduct Target Ther. 2020 Sep 14;5(1):201.
2: Chen Y, Zhang S, Wang Q, Zhang X. Tumor-recruited M2 macrophages promote gastric and breast cancer metastasis via M2 macrophage-secreted CHI3L1 protein J Hematol Oncol. 2017 Feb 1;10(1):36.
3: Lananna BV, McKee CA, King MW, Del-Aguila JL, Dimitry JM, Farias FHG, Nadarajah CJ, Xiong DD, Guo C, Cammack AJ, Elias JA, Zhang J, Cruchaga C, Musiek ES. Chi3l1/YKL-40 is controlled by the astrocyte circadian clock and regulates neuroinflammation and Alzheimer’s disease pathogenesis Sci Transl Med. 2020 Dec 16;12(574):eaax3519.
4: Chen A, Jiang Y, Li Z, Wu L, Santiago U, Zou H, Cai C, Sharma V, Guan Y, McCarl LH, Ma J, Wu YL, Michel J, Shi Y, Konnikova L, Amankulor NM, Zinn PO, Kohanbash G, Agnihotri S, Lu S, Lu X, Sun D, Gittes GK, Wang Q, Xiao X, Yimlamai D, Pollack IF, Camacho CJ, Hu B. Chitinase-3-like 1 protein complexes modulate macrophage-mediated immune suppression in glioblastoma J Clin Invest. 2021 Aug 16;131(16):e147552.
5: Puthumana J, Thiessen-Philbrook H, Xu L, Coca SG, Garg AX, Himmelfarb J, Bhatraju PK, Ikizler TA, Siew ED, Ware LB, Liu KD, Go AS, Kaufman JS, Kimmel PL, Chinchilli VM, Cantley LG, Parikh CR. Biomarkers of inflammation and repair in kidney disease progression J Clin Invest. 2021 Feb 1;131(3):e139927.
6: Böckelmann LC, Felix T, Calabrò S, Schumacher U. YKL-40 protein expression in human tumor samples and human tumor cell line xenografts: implications for its use in tumor models Cell Oncol (Dordr). 2021 Oct;44(5):1183-1195.
7: Shan Z, Li L, Atkins CL, Wang M, Wen Y, Jeong J, Moreno NF, Feng D, Gui X, Zhang N, Lee CG, Elias JA, Lee WM, Gao B, Lam FW, An Z, Ju C. Chitinase 3-like-1 contributes to acetaminophen-induced liver injury by promoting hepatic platelet recruitment Elife. 2021 Jun 10;10:e68571.
8: Sanfilippo C, Castrogiovanni P, Imbesi R, Kazakowa M, Musumeci G, Blennow K, Zetterberg H, Di Rosa M. Sex difference in CHI3L1 expression levels in human brain aging and in Alzheimer’s disease Brain Res. 2019 Oct 1;1720:146305.
9: Görgens SW, Hjorth M, Eckardt K, Wichert S, Norheim F, Holen T, Lee S, Langleite T, Birkeland KI, Stadheim HK, Kolnes KJ, Tangen DS, Kolnes AJ, Jensen J, Drevon CA, Eckel J. The exercise-regulated myokine chitinase-3-like protein 1 stimulates human myocyte proliferation Acta Physiol (Oxf). 2016 Mar;216(3):330-45.
10: [YKL-40] Arerugi. 2017;66(8):1016-1017.

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