Human ABHD12B Protein

Product Description

Human ABHD12B Protein
Catalog number: B2011453
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 µg
Molecular Weight or Concentration: 1 mg/mL
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: ABHD12B protein (His tag), Abhydrolase domain containing 12B protein, BEM46L3 protein, c14_5314 protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Xu J, Gu W, Ji K, Xu Z, Zhu H, Zheng W. Sequence analysis and structure prediction of ABHD16A and the roles of the ABHD family members in human disease Open Biol. 2018 May;8(5):180017.
2: Chen JJ, Fan Y, Boehning D. Regulation of Dynamic Protein S-Acylation Front Mol Biosci. 2021 Apr 26;8:656440.
3: Sanders MA, Zhang H, Mladenovic L, Tseng YY, Granneman JG. Molecular Basis of ABHD5 Lipolysis Activation Sci Rep. 2017 Feb 17;7:42589.
4: Arya M, Srinivasan M, Rajasekharan R. Human alpha beta hydrolase domain containing protein 11 and its yeast homolog are lipid hydrolases Biochem Biophys Res Commun. 2017 Jun 10;487(4):875-880.
5: Lord CC, Thomas G, Brown JM. Mammalian alpha beta hydrolase domain (ABHD) proteins: Lipid metabolizing enzymes at the interface of cell signaling and energy metabolism Biochim Biophys Acta. 2013 Apr;1831(4):792-802.
6: Bononi G, Tuccinardi T, Rizzolio F, Granchi C. α/β-Hydrolase Domain (ABHD) Inhibitors as New Potential Therapeutic Options against Lipid-Related Diseases J Med Chem. 2021 Jul 22;64(14):9759-9785.
7: Hussain Z, Uyama T, Tsuboi K, Ueda N. Mammalian enzymes responsible for the biosynthesis of N-acylethanolamines Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Dec;1862(12):1546-1561.
8: Thomas G, Brown AL, Brown JM. In vivo metabolite profiling as a means to identify uncharacterized lipase function: recent success stories within the alpha beta hydrolase domain (ABHD) enzyme family Biochim Biophys Acta. 2014 Aug;1841(8):1097-101.
9: Vijayakumar A, Vijayaraj P, Vijayakumar AK, Rajasekharan R. The Arabidopsis ABHD11 Mutant Accumulates Polar Lipids in Leaves as a Consequence of Absent Acylhydrolase Activity Plant Physiol. 2016 Jan;170(1):180-93.
10: Baggelaar MP, den Dulk H, Florea BI, Fazio D, Bernabò N, Raspa M, Janssen APA, Scavizzi F, Barboni B, Overkleeft HS, Maccarrone M, van der Stelt M. ABHD2 Inhibitor Identified by Activity-Based Protein Profiling Reduces Acrosome Reaction ACS Chem Biol. 2019 Oct 18;14(10):2295-2304.

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