High HAMA Serum

Sale!
High HAMA Serum

High HAMA Serum

Price range: $595.00 through $7,950.00

Catalog #: S2010006
High HAMA Serum is a serum sample with an anti-mouse antibodies (HAMA) titer established with a cleared HAMA ELISA method. This sample is to be used to test HAMA interference in immunoassays.

SKU: S2010006 Categories: , Tag:

Product Description

4.9/5 - (24 votes)

High HAMA Serum

Catalog number: S2010006
Lot number: Batch Dependent
Expiration date: Batch Dependent
Volume: 1 mL
Appearance: Yellow orange
Matrix: Human serum
Storage: At -20°C or lower. Avoid repeated freeze-thaw cycles. Aliquot as needed.
Keywords HAMA sample, Human Anti-Mouse Antibodies serum, High HAMA plasma

 

About HAMA

Immunoassays rely heavily on mouse antibodies for the detection of various analytes. The accuracy of these assays can, however, suffer when samples contain human anti-mouse antibodies (HAMA). Indeed, HAMA are often associated with inaccurate results because they can bind to both capture and detection antibodies and can generate non-specific signals. This so-called HAMA effect is major interference issue. Assessing the tolerance of an immunoassay to HAMA and mitigating it is very important important during research and development.

References

  • Reinsberg J. (1996). Different efficacy of various blocking reagents to eliminate interferences by human antimouse antibodies with a two-site immunoassay. Clin Biochem. 1996 Apr;29(2):145-8.
  • Bolstad N, Warren DJ, Nustad K. Heterophilic antibody interference in immunometric assays. Best Pract Res Clin Endocrinol Metab. 2013 Oct;27(5):647-61.
  • Lippi G, Aloe R, Meschi T, Borghi L, Cervellin G. Interference from heterophilic antibodies in troponin testing. Case report and systematic review of the literature. Clin Chim Acta. 2013 Nov 15;426:79-84.
  • Kawasaki H, Suzuki T, Ito K, Takahara T, Goto-Inoue N, Setou M, Sakata K, Ishida N. Minos-insertion mutant of the Drosophila GBA gene homologue showed abnormal phenotypes of climbing ability, sleep and life span with accumulation of hydroxy-glucocerebroside. Gene. 2017 May 30;614:49-55.
  • Hull B. Aberrantly elevated TSH level due to human anti-mouse antibodies (HAMA) interference with thyrotropin assay. J S C Med Assoc. 2012 Feb;108(1):12-3.
  • Degn SE, Andersen SH, Jensen L, Thiel S, Jensenius JC. Assay interference caused by antibodies reacting with rat kappa light-chain in human sera. J Immunol Methods. 2011 Sep 30;372(1-2):204-8.

Products Related to HAMA High Serum

HAMA Interference Kit

HAMA Blocking Reagent (Affinity Purified)

Additional Information

Weight 48 oz
Dimensions 8 × 7 × 6 in
Concentration

600-799 (ng/mL), 800-999 (ng/mL), 1000-1499 (ng/mL), 1500-1999 (ng/mL), 2000-2499 (ng/mL), 2500-4999 (ng/mL), 5000-7499 (ng/mL), >10000 ng/mL
4.9/5 - (24 votes)

Several ways to order Molecular Depot products:

1- Order online using our website’s automated shopping cart and checkout system (available 24/7).

2- Order by email: info@moleculardepot.com (we accept electronic PO, available 24/7).

3- Order by Live Chat.

4- Order by Fax: 1-858-437-9884 (available 24/7).

 

Related products