Heptakis(6-deoxy-6-thio)-beta-cyclodextrin

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Heptakis(6-deoxy-6-thio)-beta-cyclodextrin
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Heptakis(6-deoxy-6-thio)-beta-cyclodextrin

Original price was: $1,795.00.Current price is: $895.00.

Catalog Number: B2027375 (100 mg)
Heptakis(6-deoxy-6-thio)-beta-cyclodextrin is a symmetrically modified beta-cyclodextrin derivative featuring seven primary thiol groups replacing the C-6 hydroxyl groups on its glucose subunits. The reactive mercapto groups enable facile chemical conjugation, gold surface immobilization, and the formation of advanced supramolecular assemblies. Featuring a hydrophobic inner cavity, this compound serves as a versatile functionalized scaffold for nanotechnology and host-guest inclusion complexation. Custom bulk amounts of this product are available upon request.

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Product Description

5/5 - (1 vote)

Heptakis(6-deoxy-6-thio)-beta-cyclodextrin
Catalog number: B2027375
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 mg
Molecular Weight or Concentration: 1247.4
Supplied as: Chemicals
Storage: 2-8 ËšC
Keywords: Heptakis-(6-Mercapto-6-deoxy)-beta-Cyclodextrin, Per-6-thio-β-cyclodextrin, Heptakis(6-deoxy-6-thio)cyclomaltoheptaose

References:
1. Ashton, P. R., Ellwood, P., Staton, I., & Stoddart, J. F. (1991). Synthesis and characterization of per-6-thio-β-cyclodextrin. Journal of Organic Chemistry, 56(26), 7274-7280.
2. Chmurski, K., & Defaye, J. (1997). High-yield synthesis of heptakis(6-deoxy-6-thio)-β-cyclodextrin. Tetrahedron Letters, 38(42), 7365-7368.
3. Rojas, M. T., Königer, R., Stoddart, J. F., & Kaifer, A. E. (1995). Supported monolayers containing β-cyclodextrin units. Journal of the American Chemical Society, 117(1), 336-343.
4. Bentahir, A., Garcia Fernandez, J. M., & Defaye, J. (2002). Efficient synthesis of per-(6-deoxy-6-thio)cyclodextrins. Carbohydrate Research, 337(7), 601-608.
5. Ling, C. C., & Darcy, R. (1998). The synthesis of per-functionalised cyclodextrins. Journal of the Chemical Society, Perkin Transactions 1, (9), 1483-1504.
6. Mazzaglia, A., Donohue, R., Ravoo, B. J., & Darcy, R. (2001). Amphiphilic cyclodextrins with thioether linkages. European Journal of Organic Chemistry, 2001(9), 1715-1721.
7. Kahn, A., & Bernkop-Schnürch, A. (2015). Thiolated cyclodextrins: Synthesis and biological evaluation. International Journal of Pharmaceutics, 484(1-2), 156-164.
8. Loftsson, T., & Duchêne, D. (2007). Cyclodextrins and their pharmaceutical applications. International Journal of Pharmaceutics, 329(1-2), 1-11.
9. Szejtli, J. (1998). Introduction and general overview of cyclodextrin chemistry. Chemical Reviews, 98(5), 1743-1754.
10. Davis, M. E., & Brewster, M. E. (2004). Cyclodextrin-based pharmaceutics: past, present and future. Nature Reviews Drug Discovery, 3(12), 1023-1035.
Heptakis(6-deoxy-6-thio)-beta-cyclodextrin

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Additional Information

Weight 0.15 oz
Dimensions 2 × 0.5 × 0.5 in
5/5 - (1 vote)

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