HAT Assay Buffer 5X (Biotechnology Grade)


Catalog Number: B2010130 (2 mL)
HAT Assay Buffer 5X is a high quality research product used as optimized buffer for histone acetyltransferase (HAT) assays. Custom bulk orders of this product are available upon request.

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HAT Assay Buffer 5X
Catalog number: B2010130
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 2 mL
pH: 8
Supplied as: 5X Concentrate (Dilute 1:5 before use)
Appearance: Clear solution
Applications: optimized buffer for histone acetyltransferase (HAT) assays.
Storage: −20°C
Keywords: HAT buffer, histone acetyltransferase assay, cell-based assay development
Grade: Biotechnology grade. All components are highly pure (minimum 99%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered on a 0.22 um.

1: Su J, Wang F, Cai Y, Jin J. The Functional Analysis of Histone
Acetyltransferase MOF in Tumorigenesis. Int J Mol Sci. 2016 Jan 14;17(1):99.

2: Voss AK, Thomas T. Histone Lysine and Genomic Targets of Histone
Acetyltransferases in Mammals. Bioessays. 2018 Oct;40(10):e1800078.

3: Baell JB, Miao W. Histone acetyltransferase inhibitors: where art thou?
Future Med Chem. 2016 Sep;8(13):1525-8.

4: Yin Z, Chen C, Yang J, Feng W, Liu X, Zuo R, Wang J, Yang L, Zhong K, Gao C,
Zhang H, Zheng X, Wang P, Zhang Z. Histone acetyltransferase MoHat1 acetylates
autophagy-related proteins MoAtg3 and MoAtg9 to orchestrate functional
appressorium formation and pathogenicity in Magnaporthe oryzae.
Autophagy. 2019 Jul;15(7):1234-1257.

5: Dubey A, Lee J, Kwon S, Lee YH, Jeon J. A MYST family histone
acetyltransferase, MoSAS3, is required for development and pathogenicity in the
rice blast fungus. Mol Plant Pathol. 2019 Nov;20(11):1491-1505.

6: Lasko LM, Jakob CG, Edalji RP, Qiu W, Montgomery D, Digiammarino EL, Hansen
TM, Risi RM, Frey R, Manaves V, Shaw B, Algire M, Hessler P, Lam LT, Uziel T,
Faivre E, Ferguson D, Buchanan FG, Martin RL, Torrent M, Chiang GG, Karukurichi
K, Langston JW, Weinert BT, Choudhary C, de Vries P, Van Drie JH, McElligott D,
Kesicki E, Marmorstein R, Sun C, Cole PA, Rosenberg SH, Michaelides MR, Lai A,
Bromberg KD. Discovery of a selective catalytic p300/CBP inhibitor that targets
lineage-specific tumours. Nature. 2017 Oct 5;550(7674):128-132.

7: Martin BJ, McBurney KL, Maltby VE, Jensen KN, Brind’Amour J, Howe LJ. Histone
H3K4 and H3K36 Methylation Independently Recruit the NuA3 Histone
Acetyltransferase in Saccharomyces cerevisiae. Genetics. 2017

8: Han J, Lachance C, Ricketts MD, McCullough CE, Gerace M, Black BE, Côté J,
Marmorstein R. The scaffolding protein JADE1 physically links the
acetyltransferase subunit HBO1 with its histone H3-H4 substrate. J Biol Chem.
2018 Mar 23;293(12):4498-4509.

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Additional information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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