Guanidine Hydrochloride Solution 6M

Description

Guanidine hydrochloride solution, 6M
Catalog number: B2010142
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 50 mL
pH: na
Supplied as: Ready-to-use solution
Appearance: Clear solution
Applications: stock solution for the denaturation of proteins thanks to its ability to disrupt the hydrogen bonds between the polar side chains of amino residues. Guanidine chloride-promoted protein denaturation can be used in protein purification and analysis as well as isolation of protein-bound ligands.
Storage: Room temperature
Keywords: Aminoformamidine hydrochloride, GuHCl, Guanidinium chloride, Guanidium chloride
Grade: Biotechnology grade. All components are highly pure (minimum 99%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered on a 0.22 um.

References:
1: Terenteva EA, Apyari VV, Dmitrienko SG, Garshev AV, Volkov PA, Zolotov YA.
Determination of pyrophosphate and sulfate using polyhexamethylene guanidine
hydrochloride-stabilized silver nanoparticles. Talanta. 2018 Apr 1;180:346-351.

2: Carvalho FA, Alves FR, Carvalho JW, Tabak M. Guanidine hydrochloride and urea
effects upon thermal stability of Glossoscolex paulistus hemoglobin (HbGp). Int
J Biol Macromol. 2015 Mar;74:18-28.

3: Vernaglia BA, Huang J, Clark ED. Guanidine hydrochloride can induce amyloid
fibril formation from hen egg-white lysozyme. Biomacromolecules. 2004 Jul-
Aug;5(4):1362-70.

4: Ngernna S, Chim-Ong A, Roobsoong W, Sattabongkot J, Cui L, Nguitragool W.
Efficient synchronization of Plasmodium knowlesi in vitro cultures using
guanidine hydrochloride. Malar J. 2019 Apr 25;18(1):148.

5: Schlegel A, Immelmann A, Kempf C. Virus inactivation of plasma-derived
proteins by pasteurization in the presence of guanidine hydrochloride.
Transfusion. 2001 Mar;41(3):382-9.

6: Emadi S, Behzadi M. A comparative study on the aggregating effects of
guanidine thiocyanate, guanidine hydrochloride and urea on lysozyme aggregation.
Biochem Biophys Res Commun. 2014 Aug 8;450(4):1339-44.

7: Heller WT. Comparison of the thermal denaturing of human serum albumin in the
presence of guanidine hydrochloride and 1-butyl-3-methylimidazolium ionic
liquids. J Phys Chem B. 2013 Feb 28;117(8):2378-83.

8: Raskar T, Koh CY, Niebling S, Kini RM, Hosur MV. X-ray crystallographic
analysis of time-dependent binding of guanidine hydrochloride to HEWL: First
steps during protein unfolding. Int J Biol Macromol. 2019 Feb 1;122:903-913.

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