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Fluorescent Plasmin Substrate

$595.00

Catalog Number: B2011470 (5 mg)
Fluorescent Plasmin Substrate is a high quality fluorescent plasmin substrate (H-D-Val-Leu-Lys-AFC). This product has been used as used to stain cytoplasm and erythrocytes. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

Live enquiry about this product via Text/SMS: 1-858-900-3210.

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SKU: B2011470 Categories: ,

Description

Fluorescent Plasmin Substrate
Catalog number: B2011470
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 mg
Molecular Weight or Concentration: 569.6 g/mol
Supplied as: Lyophilized
Applications: used to stain cytoplasm and erythrocytes
Storage: -20 °C
Keywords: Plasmin Substrate, fluorescent (H-D-Val-Leu-Lys-AFC)
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Sharma V, Kumar S, Sahni G. Kringles of substrate plasminogen provide a ‘catalytic switch’ in plasminogen to plasmin turnover by Streptokinase Biochem J. 2020 Mar 13;477(5):953-970.
2: Mindel E, Weiss R, Bushi D, Gera O, Orion D, Chapman J, Shavit-Stein E. Increased brain plasmin levels following experimental ischemic stroke in male mice J Neurosci Res. 2021 Mar;99(3):966-976.
3: Lawson DE, Mitchell GA, Huseby RM. A sensitive fluorescent assay for determining alpha2-plasmin inhibitor using a synthetic substrate Thromb Res. 1979 Feb-Mar;14(2-3):323-32.
4: Leung K. Cy5.5-GGSGRSANAK(Fitc)C-poly-L-lysine-methoxy polyethylene glycol 2009 Jan 5 [updated 2009 Mar 3]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013.
5: Pierzchala PA, Dorn CP, Zimmerman M. A new fluorogenic substrate for plasmin Biochem J. 1979 Dec 1;183(3):555-9.
6: Backes BJ, Harris JL, Leonetti F, Craik CS, Ellman JA. Synthesis of positional-scanning libraries of fluorogenic peptide substrates to define the extended substrate specificity of plasmin and thrombin Nat Biotechnol. 2000 Feb;18(2):187-93.
7: Zeng Z, Nallan Chakravarthula T, Muralidharan C, Hall A, Linnemann AK, Alves NJ. Fluorescently conjugated annular fibrin clot for multiplexed real-time digestion analysis J Mater Chem B. 2021 Nov 24;9(45):9295-9307.
8: Boxrud PD, Fay WP, Bock PE. Streptokinase binds to human plasmin with high affinity, perturbs the plasmin active site, and induces expression of a substrate recognition exosite for plasminogen J Biol Chem. 2000 May 12;275(19):14579-89.
9: Bikker FJ, Koop G, Leusink NB, Nazmi K, Kaman WE, Brand HS, Veerman EC. Tailor made plasmin substrates as potential diagnostic tool to test for mastitis Vet Res Commun. 2014 Dec;38(4):271-7.
10: Oliva ML, Andrade SA, Juliano MA, Sallai RC, Torquato RJ, Sampaio MU, Pott VJ, Sampaio CA. Kinetic characterization of factor Xa binding using a quenched fluorescent substrate based on the reactive site of factor Xa inhibitor from Bauhinia ungulata seeds Curr Med Chem. 2003 Jul;10(13):1085-93.

Products Related to Fluorescent Plasmin Substrate can be found at Substrates

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