Fibroblast Growth Factor 23 (Human, Recombinant)
$395.00
Catalog Number: B2010302 (10 ug)
Fibroblast Growth Factor 23 (Human, Recombinant) is a high quality research product used as highly pure Fibroblast Growth Factor 23 (Human, Recombinant) expressed in E. coli. This protein acts as a unique FGF subfamily member that functions as as a hormone and requires α-Klotho to signal through the canonical FGFR, inducing hypertrophy and mineralization during chondrogenesis. Custom bulk orders of this product are available upon request.
In stock
Description
Fibroblast Growth Factor 23 (Human, Recombinant)
Catalog number: B2010302
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 10 ug
pH: 7.4 upon reconstitution
Supplied as: Lyophilized Powder
Appearance: Powder
Applications: highly pure Fibroblast Growth Factor 23 (Human, Recombinant) expressed in E. coli. This protein acts as a unique FGF subfamily member that functions as as a hormone and requires α-Klotho to signal through the canonical FGFR, inducing hypertrophy and mineralization during chondrogenesis.
Storage: -20C
Keywords: rHuFGF-23; Phosphatonin; Tumor-derived hypophosphatemia-inducing factor
Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.
References:
1: Ornitz DM, Itoh N. Fibroblast growth factors. Genome Biol.
2001;2(3):REVIEWS3005.
2: Degirolamo C, Sabbà C, Moschetta A. Therapeutic potential of the endocrine
fibroblast growth factors FGF19, FGF21 and FGF23. Nat Rev Drug Discov. 2016
Jan;15(1):51-69.
3: Pawlikowski B, Vogler TO, Gadek K, Olwin BB. Regulation of skeletal muscle
stem cells by fibroblast growth factors. Dev Dyn. 2017 May;246(5):359-367.
4: Turner N, Grose R. Fibroblast growth factor signalling: from development to
cancer. Nat Rev Cancer. 2010 Feb;10(2):116-29.
5: Li Q, Zhai Z, Li J. Fibroblast growth factor homologous factors are potential
ion channel modifiers associated with cardiac arrhythmias. Eur J Pharmacol. 2020
Mar 15;871:172920.
6: Thomas KA. Fibroblast growth factors. FASEB J. 1987 Dec;1(6):434-40.
7: Tucker B, Li H, Long X, Rye KA, Ong KL. Fibroblast growth factor 21 in non-
alcoholic fatty liver disease. Metabolism. 2019 Dec;101:153994.
8: Su X, Kong Y, Peng D. Fibroblast growth factor 21 in lipid metabolism and
non-alcoholic fatty liver disease. Clin Chim Acta. 2019 Nov;498:30-37.
9: Terwisscha van Scheltinga AF, Bakker SC, Kahn RS, Kas MJ. Fibroblast growth
factors in neurodevelopment and psychopathology. Neuroscientist. 2013
Oct;19(5):479-94.
10: Braun S, auf dem Keller U, Steiling H, Werner S. Fibroblast growth factors
in epithelial repair and cytoprotection. Philos Trans R Soc Lond B Biol Sci.
2004 May 29;359(1445):753-7.
Products Related to Fibroblast Growth Factor 23 (Human, Recombinant) : Proteins
Additional information
Weight | 48 oz |
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Dimensions | 8 × 8 × 8 in |
Ordering Information
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