Factor XI Deficient Human Plasma


Catalog Number: B2012590 (5 mL)
Factor XI Deficient Human Plasma is a high quality plasma prepared from citrated pooled human plasma that has been immuno-depleted of Factor XI. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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SKU: B2012590 Categories: , Tag:


Factor XI Deficient Human Plasma
Catalog number: B2012590
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 mL
Molecular Weight or Concentration: N/A
Supplied as: Plasma
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: FXI Deficient Plasma
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Lewandowska MD, Connors JM. Factor XI Deficiency Hematol Oncol Clin North Am. 2021 Dec;35(6):1157-1169.
2: Mohammed BM, Cheng Q, Matafonov A, Monroe DM, Meijers JCM, Gailani D. Factor XI promotes hemostasis in factor IX-deficient mice J Thromb Haemost. 2018 Oct;16(10):2044-2049.
3: Dai L, Mitchell M, Savidge G, Alhaq A. The profibrinolytic effect of plasma thrombomodulin in factor XI deficiency and its implications in hemostasis J Thromb Haemost. 2004 Dec;2(12):2200-4.
4: Visser M, van Oerle R, Ten Cate H, Laux V, Mackman N, Heitmeier S, Spronk HMH. Plasma Kallikrein Contributes to Coagulation in the Absence of Factor XI by Activating Factor IX Arterioscler Thromb Vasc Biol. 2020 Jan;40(1):103-111.
5: Duga S, Salomon O. Factor XI Deficiency Semin Thromb Hemost. 2009 Jun;35(4):416-25.
6: Mooberry MJ, Bradford R, Hobl EL, Lin FC, Jilma B, Key NS. Procoagulant microparticles promote coagulation in a factor XI-dependent manner in human endotoxemia J Thromb Haemost. 2016 May;14(5):1031-42.
7: Ling G, Kagdi H, Subel B, Chowdary P, Gomez K. Safety and efficacy of factor XI (FXI) concentrate use in patients with FXI deficiency: a single-centre experience of 19 years Haemophilia. 2016 May;22(3):411-8.
8: Kasonga F, Feugray G, Chamouni P, Barbay V, Fresel M, Chretien MH, Brunel S, Le Cam Duchez V, Billoir P. Evaluation of thrombin generation assay in factor XI deficiency Clin Chim Acta. 2021 Dec;523:348-354.
9: Pike GN, Cumming AM, Hay CR, Sempasa B, Sutherland M, Thachil J, Burthem J, Bolton-Maggs PH. In vitro comparison of the effect of two factor XI (FXI) concentrates on thrombin generation in major FXI deficiency Haemophilia. 2016 May;22(3):403-10.
10: Minami H, Nogami K, Yada K, Ogiwara K, Furukawa S, Soeda T, Kitazawa T, Shima M. Emicizumab, the bispecific antibody to factors IX/IXa and X/Xa, potentiates coagulation function in factor XI-deficient plasma in vitro J Thromb Haemost. 2019 Jan;17(1):126-137.

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