EGFR Monoclonal Antibody

Product Description

EGFR Monoclonal Antibody
Catalog number: B2017745
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 µg
Molecular Weight or Concentration: N/A
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: -20°C
Keywords: Epidermal Growth Factor Receptor, ErbB-1, HER1
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Misale S, Yaeger R, Hobor S, Scala E, Janakiraman M, Liska D, Valtorta E, Schiavo R, Buscarino M, Siravegna G, Bencardino K, Cercek A, Chen CT, Veronese S, Zanon C, Sartore-Bianchi A, Gambacorta M, Gallicchio M, Vakiani E, Boscaro V, Medico E, Weiser M, Siena S, Di Nicolantonio F, Solit D, Bardelli A. Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer Nature. 2012 Jun 28;486(7404):532-6.
2: Gandullo-Sánchez L, Pandiella A. An anti-EGFR antibody-drug conjugate overcomes resistance to HER2-targeted drugs Cancer Lett. 2023 Feb 1;554:216024.
3: Yi CH, Ruan CP, Wang H, Xu XY, Zhao YP, Fang M, Ji J, Gu X, Gao CF. Function characterization of a glyco-engineered anti-EGFR monoclonal antibody cetuximab in vitro Acta Pharmacol Sin. 2014 Nov;35(11):1439-46.
4: Yao Z, Peng P, Xu D, Zhou X, Pan Z, Li Z, Yao J, Chen J. EGFR inhibitor C225 Increases the Radio-Sensitivity of Human Breast Cancer Cells Asian Pac J Cancer Prev. 2019 Jan 25;20(1):311-319.
5: Makabe K, Yokoyama T, Uehara S, Uchikubo-Kamo T, Shirouzu M, Kimura K, Tsumoto K, Asano R, Tanaka Y, Kumagai I. Anti-EGFR antibody 528 binds to domain III of EGFR at a site shifted from the cetuximab epitope Sci Rep. 2021 Mar 11;11(1):5790.
6: Ciardiello D, Mauri G, Sartore-Bianchi A, Siena S, Zampino MG, Fazio N, Cervantes A. The role of anti-EGFR rechallenge in metastatic colorectal cancer, from available data to future developments: A systematic review Cancer Treat Rev. 2024 Mar;124:102683.
7: Chopra A. (111)In-Labeled anti-epidermal growth factor receptor human monoclonal antibody 048-006 2012 Oct 10 [updated 2012 Nov 8]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013.
8: Ahdi Khosroshahi S, Farajnia S, Ghiamirad M, Tanomand A, Veisi K, Rahbarnia L, Akbari B. Development and evaluation of a single domain antibody against human epidermal growth factor receptor (EGFR) Protein Expr Purif. 2016 Apr;120:59-64.
9: Okada Y, Kimura T, Nakagawa T, Okamoto K, Fukuya A, Goji T, Fujimoto S, Sogabe M, Miyamoto H, Muguruma N, Tsuji Y, Okahisa T, Takayama T. EGFR Downregulation after Anti-EGFR Therapy Predicts the Antitumor Effect in Colorectal Cancer Mol Cancer Res. 2017 Oct;15(10):1445-1454.
10: Singer J, Fazekas J, Wang W, Weichselbaumer M, Matz M, Mader A, Steinfellner W, Meitz S, Mechtcheriakova D, Sobanov Y, Willmann M, Stockner T, Spillner E, Kunert R, Jensen-Jarolim E. Generation of a canine anti-EGFR (ErbB-1) antibody for passive immunotherapy in dog cancer patients Mol Cancer Ther. 2014 Jul;13(7):1777-1790.

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