Des-Arg9-[Leu8]-Bradykinin

Product Description

Des-Arg9-[Leu8]-Bradykinin
Catalog number: MDP0422
CAS Number: 86933-74-6
Sequence: Arg-Pro-Pro-Gly-Phe-Ser-Pro-Leu . AcOH . 3H2O
Amount: 5 mg
Molecular Weight: 870 g/mol
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: -20 °C
WARNING: For in vitro Research Use Only. NOT for use on humans or animals.
Grade: Biotechnology grade. All products are highly pure.

References:
1: Farias NC, Feres T, Paiva AC, Paiva TB. Lys-[Leu8,des-Arg9]-bradykinin blocks lipopolysaccharide-induced SHR aorta hyperpolarization by inhibition of Ca(++)- and ATP-dependent K+ channels Eur J Pharmacol. 2004 Sep 13;498(1-3):163-9.
2: Rupniak NM, Boyce S, Webb JK, Williams AR, Carlson EJ, Hill RG, Borkowski JA, Hess JF. Effects of the bradykinin B1 receptor antagonist des-Arg9[Leu8]bradykinin and genetic disruption of the B2 receptor on nociception in rats and mice Pain. 1997 May;71(1):89-97.
3: Kaygısız Z, Kaygısız B, Kılınç E. The effect of Des-Arg9-bradykinin and bradykinin-potentiating peptide C on isolated rat hearts Acta Physiol Hung. 2013 Sep;100(3):280-8.
4: Hu DE, Fan TP. [Leu8]des-Arg9-bradykinin inhibits the angiogenic effect of bradykinin and interleukin-1 in rats Br J Pharmacol. 1993 May;109(1):14-7.
5: Eric J, Bkaily G, Bkaily GB, Volkov L, Gabra BH, Sirois P. Des-Arg9-bradykinin increases intracellular Ca2+ in bronchoalveolar eosinophils from ovalbumin-sensitized and -challenged mice Eur J Pharmacol. 2003 Aug 15;475(1-3):129-37.
6: Odya CE, Carlin RJ, Yapa RD, Soltani-Tehrani B. Immunoassays for des-Arg9-bradykinin J Immunoassay. 1993 Dec;14(4):227-40.
7: Alikhani M, Javadi A, Aalikhani M. Des-Arg9 bradykinin and bradykinin potentially trigger cytokine storm in patients with COVID-19 Iran J Immunol. 2021 Mar;18(1):93-94.
8: Cabrini DA, Calixto JB. Characterization of des-Arg9-bradykinin-induced contraction in guinea-pig gallbladder in vitro Eur J Pharmacol. 1997 Jul 16;331(1):31-8.
9: Marsh KA, Hill SJ. Des-Arg9-bradykinin-induced increases in intracellular calcium ion concentration in single bovine tracheal smooth muscle cells Br J Pharmacol. 1994 Jul;112(3):934-8.
10: Sheikh IA, Kaplan AP. Studies of the digestion of bradykinin, Lys-bradykinin, and des-Arg9-bradykinin by angiotensin converting enzyme Biochem Pharmacol. 1986 Jun 15;35(12):1951-6.

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