[D-Pro4,D-Trp7,9]-Substance P (4-11)

Product Description

[D-Pro4,D-Trp7,9]-Substance P (4-11)
Catalog number: MDP0485
CAS Number: 117399-93-6
Sequence: D-Pro-Gln-Gln-D-Trp-Phe-D-Trp-Leu-Met-NH2
Amount: 500 ug
Molecular Weight: 1134.4 g/mol
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: -20 °C
WARNING: For in vitro Research Use Only. NOT for use on humans or animals.
Grade: Biotechnology grade. All products are highly pure.

References:
1: Bailey SJ, Jordan CC. A study of [D-Pro2, D-Phe7, D-Trp9]-substance P and [D-Trp7,9]-substance P as tachykinin partial agonists in the rat colon Br J Pharmacol. 1984 Jun;82(2):441-51.
2: Köller G, Bienert M, Niedrich H, Bergmann J, Mezö I, Oehme P. Synthesis of substance P antagonists: [D-Pro4, D-Trp7,9,Nle11]-substance P(4-11) Pharmazie. 1984 Jan;39(1):65-7.
3: Bailey SJ, Lippe IT, Holzer P. Effect of the tachykinin antagonist, [D-Pro4, D-Trp7,9,10] substance P-(4-11), on tachykinin- and histamine-induced inositol phosphate generation in intestinal smooth muscle Naunyn Schmiedebergs Arch Pharmacol. 1987 Mar;335(3):296-300.
4: von Schrenck T, Wang LH, Coy DH, Villanueva ML, Mantey S, Jensen RT. Potent bombesin receptor antagonists distinguish receptor subtypes Am J Physiol. 1990 Sep;259(3 Pt 1):G468-73.
5: Couture R, Gupta A, Kérouac R, Escher E, Regoli D. Spinal actions of substance P analogues on cardiovascular responses in the rat: a structure-activity analysis Can J Physiol Pharmacol. 1987 Mar;65(3):412-8.
6: Vaught JL, Scott R. Species differences in the behavioral toxicity produced by intrathecal substance P antagonists: relationship to analgesia Life Sci. 1987 Jan 12;40(2):175-81.
7: Bailey SJ, Featherstone RL, Jordan CC, Morton IK. An examination of the pharmacology of two substance P antagonists and the evidence for tachykinin receptor subtypes Br J Pharmacol. 1986 Jan;87(1):79-85.
8: Charlton CG, Helke CJ. Characterization and segmental distribution of 125I-Bolton-Hunter-labeled substance P binding sites in rat spinal cord J Neurosci. 1985 May;5(5):1293-9.
9: Gulati N, Mathison R, Huggel H, Regoli D, Bény JL. Effects of neurokinins on the isolated pig coronary artery Eur J Pharmacol. 1987 Jun 4;137(2-3):149-54.
10: Featherstone RL, Fosbraey P, Morton IK. A comparison of the effects of three substance P antagonists on tachykinin-stimulated [3H]-acetylcholine release in the guinea-pig ileum Br J Pharmacol. 1986 Jan;87(1):73-7.

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