Cystatin D (Human, Highly Pure)

Description

Cystatin D (Human, Highly Pure)
Catalog number: B2010472
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 ug
Molecular Weight or Concentration: 15.2 kDa
Supplied as: Lyophilized Powder
Appearance: Powder
Applications: highly pure human Cystatin D (produced in HEK293 cells). Cystatin D is a natual inhibitor of papain-like peptidases.
Storage: -20°C
Keywords: CST5, MGC71922
Grade: Biotechnology grade. All solid components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Shu Y, Chang Y, Wu H, Li J, Cao B, Sun X, Wang J, Peng L, Hu X, Yu X, Qiu W.
Serum cystatin C and anti-N-methyl-D-aspartate receptor encephalitis. Acta
Neurol Scand. 2018 May;137(5):515-522.

2: Peng Q, Zhao J, Wang P, Huang C, Chen B, Song J, Xu G. Expressions of plasma
cystatin C, D-dimer and hypersensitive C-reactive protein in patients with
intracranial progressive hemorrhagic injury after craniocerebral injury, and
their clinical significance. Arq Neuropsiquiatr. 2019 Jul 15;77(6):381-386.

3: Ferrer-Mayorga G, Alvarez-Díaz S, Valle N, De Las Rivas J, Mendes M, Barderas
R, Canals F, Tapia O, Casal JI, Lafarga M, Muñoz A. Cystatin D locates in the
nucleus at sites of active transcription and modulates gene and protein
expression. J Biol Chem. 2015 Oct 30;290(44):26533-48.

4: Laurent-Matha V, Huesgen PF, Masson O, Derocq D, Prébois C, Gary-Bobo M,
Lecaille F, Rebière B, Meurice G, Oréar C, Hollingsworth RE, Abrahamson M,
Lalmanach G, Overall CM, Liaudet-Coopman E. Proteolysis of cystatin C by
cathepsin D in the breast cancer microenvironment. FASEB J. 2012
Dec;26(12):5172-81.

5: Alvarez-Díaz S, Valle N, García JM, Peña C, Freije JM, Quesada V, Astudillo
A, Bonilla F, López-Otín C, Muñoz A. Cystatin D is a candidate tumor suppressor
gene induced by vitamin D in human colon cancer cells. J Clin Invest. 2009
Aug;119(8):2343-58.

6: Hill LJ, Di Pietro V, Hazeldine J, Davies D, Toman E, Logan A, Belli A.
Cystatin_D (CST5): An ultra-early inflammatory biomarker of traumatic brain
injury. Sci Rep. 2017 Jul 10;7(1):5002.

7: Deng Y, Ma J, Hou Y, Zhou D, Hou T, Li J, Liang S, Tan N, Chen C. Combining
Serum Cystatin C and Urinary N-Acetyl-Beta-D-Glucosaminidase Improves the
Precision for Acute Kidney Injury Diagnosis after Resection of Intracranial
Space-Occupying Lesions. Kidney Blood Press Res. 2020;45(1):142-156.

8: Nashida T, Sato R, Haga-Tsujimura M, Yoshie S, Yoshimura K, Imai A, Shimomura
H. Antigen-presenting cells in parotid glands contain cystatin D originating
from acinar cells. Arch Biochem Biophys. 2013 Feb 1;530(1):32-9.
9: Ho J, Tangri N, Komenda P, Kaushal A, Sood M, Brar R, Gill K, Walker S,
MacDonald K, Hiebert BM, Arora RC, Rigatto C. Urinary, Plasma, and Serum
Biomarkers’ Utility for Predicting Acute Kidney Injury Associated With Cardiac
Surgery in Adults: A Meta-analysis. Am J Kidney Dis. 2015 Dec;66(6):993-1005.

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