Coumarin-Quinone Conjugate


Catalog Number: B2012810 (500 ug)
Coumarin-Quinone Conjugate is a high quality fluorescent substrate for NADH:ubiquinone oxidoreductases. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Coumarin-Quinone Conjugate
Catalog number: B2012810
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 500 ug
Molecular Weight or Concentration: 423.5 g/mol
Supplied as: Lyophilized Powder
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: A fluorescent substrate for NADH:ubiquinone oxidoreductases
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

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2: Oprych D, Strehmel B. Mediated Generation of Conjugate Acid by UV and Blue Sensitizers with Upconversion Nanoparticles at 980 nm Chemistry. 2021 Mar 1;27(13):4297-4301.
3: Wefers H, Sies H. Hepatic low-level chemiluminescence during redox cycling of menadione and the menadione-glutathione conjugate: relation to glutathione and NAD(P)H:quinone reductase (DT-diaphorase) activity Arch Biochem Biophys. 1983 Jul 15;224(2):568-78.
4: Qiu ZW, Xu XT, Pan HP, Jia ZS, Ma AJ, Peng JB, Du JY, Feng N, Li BQ, Zhang XZ. Brønsted Acid-Catalyzed Formal (3+3)-Annulation of Propargylic (Aza)-para-Quinone Methides with 4-Hydroxycoumarins and 1,3-Dicarbonyl Compounds J Org Chem. 2021 May 7;86(9):6075-6089.
5: Stoffman EJ, Clive DL. The coumarin–>indole transformation–a method for preparing 4-halo-5-hydroxyindoles from coumarins Org Biomol Chem. 2009 Dec 7;7(23):4862-70.
6: Yao C, Li Y, Wang Z, Song C, Hu X, Liu S. Cytosolic NQO1 Enzyme-Activated Near-Infrared Fluorescence Imaging and Photodynamic Therapy with Polymeric Vesicles ACS Nano. 2020 Feb 25;14(2):1919-1935.
7: Talalay P. Mechanisms of induction of enzymes that protect against chemical carcinogenesis Adv Enzyme Regul. 1989;28:237-50.
8: Hueso-Falcón I, Amesty Á, Anaissi-Afonso L, Lorenzo-Castrillejo I, Machín F, Estévez-Braun A. Synthesis and biological evaluation of naphthoquinone-coumarin conjugates as topoisomerase II inhibitors Bioorg Med Chem Lett. 2017 Feb 1;27(3):484-489.
9: Aristizábal D, Gil J, Quiñones W, Durango D. Screening of Indanoyl-Type Compounds as Elicitors of Isoflavonoid Phytoalexins in Colombian Common Bean Cultivars Molecules. 2022 May 30;27(11):3500.
10: Israels LG, Israels ED. Observations on vitamin K deficiency in the fetus and newborn: has nature made a mistake? Semin Thromb Hemost. 1995;21(4):357-63.

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