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Chromogenic Caspase 8 Substrate 1

$595.00

Catalog Number: B2011411 (5 mg)
Chromogenic Caspase 8 Substrate 1 is a high quality pNA (4-nitroaniline)-derived caspase substrate used for the colorimetric detection of caspase activities. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

Live enquiry about this product via Text/SMS: 1-858-900-3210.

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SKU: B2011411 Categories: ,

Description

Chromogenic Caspase 8 Substrate 1
Catalog number: B2011411
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 mg
Molecular Weight or Concentration: 638.7 g/mol
Supplied as: Lyophilized
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords:
Caspase 8 Substrate 1, chromogenic
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: McStay GP, Green DR. Assaying caspase activity in vitro Cold Spring Harb Protoc. 2014 Jul 1;2014(7):774-7.
2: Wang Y, Zhang X, Guo Y, Li X, Guo G, Niu Z, Zhang J. Type 1 interferon aggravates lipopolysaccharide-induced sepsis through upregulating Caspase-11 and Gasdermin D J Physiol Biochem. 2021 Feb;77(1):85-92.
3: Zeng L, Smith LD. Caspase-3 colorimetric assay Biotechniques. 2002 Dec;33(6):1196-7.
4: Peterson QP, Goode DR, West DC, Botham RC, Hergenrother PJ. Preparation of the caspase-3/7 substrate Ac-DEVD-pNA by solution-phase peptide synthesis Nat Protoc. 2010 Feb;5(2):294-302.
5: Liang Y, Yan C, Schor NF. Apoptosis in the absence of caspase 3 Oncogene. 2001 Oct 4;20(45):6570-8.
6: Ryser S, Vial E, Magnenat E, Schlegel W, Maundrell K. Reconstitution of caspase-mediated cell-death signalling in Schizosaccharomyces pombe Curr Genet. 1999 Aug;36(1-2):21-8.
7: Osawa Y, Banno Y, Nagaki M, Nozawa Y, Moriwaki H, Nakashima S. Caspase activation during hepatocyte apoptosis induced by tumor necrosis factor-alpha in galactosamine-sensitized mice Liver. 2001 Oct;21(5):309-19.
8: Banjerdpongchai R, Wudtiwai B, Pompimon W. Enterocarpam-III induces human liver and breast cancer cell apoptosis via mitochondrial and caspase-9 activation Asian Pac J Cancer Prev. 2015;16(5):1833-7.
9: Van Noorden CJ. The history of Z-VAD-FMK, a tool for understanding the significance of caspase inhibition Acta Histochem. 2001 Jul;103(3):241-51.
10: Perry DK, Smyth MJ, Stennicke HR, Salvesen GS, Duriez P, Poirier GG, Hannun YA. Zinc is a potent inhibitor of the apoptotic protease, caspase-3. A novel target for zinc in the inhibition of apoptosis J Biol Chem. 1997 Jul 25;272(30):18530-3.

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