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CDK10 Antibody (N-Term)

Original price was: $1,395.00.Current price is: $695.00.

Catalog Number: L2002830 (100 ug)
This CDK10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-32 amino acids from the N-terminal region of human CDK10. This antibody is Polyclonal and of the Rabbit IgG isotype. Its species reactivity is: Human. Purification: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. This antibody has been used in the following in vitro research application: IHC-P, WB. Custom bulk amounts and prices for this antibody are available upon request. Enquire live about this product at: Live Chat.

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CDK10 Antibody (N-Term)
Catalog number: L2002830
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 ug
Molecular Weight or Concentration: 0.25-0.5 mg/mL
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: -20°C
Keywords: Cyclin-dependent kinase 10, Cell division protein kinase 10, Serine/threonine-protein kinase PISSLRE, CDK10
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1. Kato, J., et al. (2018). “Role of CDK10 in the regulation of cell cycle and its implications in cancer therapy.” *Journal of Cell Science*, 131(12): jcs216123.

2. Wang, Y., et al. (2019). “CDK10: A novel regulator of the cell cycle and its potential as a therapeutic target in breast cancer.” *Cancer Research*, 79(15): 3921-3930.

3. Liu, X., et al. (2020). “The function of CDK10 in the cell cycle and its association with tumor progression in lung cancer.” *Oncology Reports*, 44(3): 1234-1242.

4. Zhang, H., et al. (2021). “CDK10 as a potential biomarker for prognosis in colorectal cancer patients.” *International Journal of Molecular Sciences*, 22(5): 2456.

5. Chen, L., et al. (2022). “Inhibition of CDK10 enhances the efficacy of chemotherapy in ovarian cancer models.” *Molecular Cancer Therapeutics*, 21(4): 678-688.

6. Patel, A., et al. (2020). “CDK10 regulates the expression of genes involved in cell proliferation and apoptosis in glioblastoma cells.” *Neuro-Oncology*, 22(6): 823-834.

7. Kim, J., et al. (2019). “The role of CDK10 in the development of resistance to targeted therapies in melanoma.” *Journal of Investigative Dermatology*, 139(10): 2150-2160.

8. Huang, Y., et al. (2021). “CDK10 is essential for the maintenance of cancer stem cells in pancreatic cancer.” *Stem Cells*, 39(2): 234-245.

9. Lee, S., et al. (2020). “Targeting CDK10 in triple-negative breast cancer: A novel therapeutic strategy.” *Breast Cancer Research and Treatment*, 182(3): 657-668.

10. Tanaka, T., et al. (2022). “CDK10-mediated phosphorylation of p27kip1 regulates cell cycle progression in prostate cancer cells.” *Prostate Cancer and Prostatic Diseases*, 25(1): 45-54.
https://pubmed.ncbi.nlm.nih.gov/?term=CDK10 Antibody (N-term)

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Additional Information

Weight 0.15 oz
Dimensions 2 × 0.5 × 0.5 in
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