Cathepsin D and E FRET Substrate

Product Description

Cathepsin D and E FRET Substrate
Catalog number: B2011297
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: 1756.1 g/mol
Supplied as: Lyophilized
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: Fluorgenic Cathepsin D and E FRET Substrate acetate
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Kurianiuk A, Socha K, Gacko M, Błachnio-Zabielska A, Karwowska A. The Relationship between the Concentration of Cathepsin A, D, and E and the Concentration of Copper and Zinc, and the Size of the Aneurysmal Enlargement in the Wall of the Abdominal Aortic Aneurysm Ann Vasc Surg. 2019 Feb;55:182-188.
2: Ashraf Y, Mansouri H, Laurent-Matha V, Alcaraz LB, Roger P, Guiu S, Derocq D, Robin G, Michaud HA, Delpech H, Jarlier M, Pugnière M, Robert B, Puel A, Martin L, Landomiel F, Bourquard T, Achour O, Fruitier-Arnaudin I, Pichard A, Deshayes E, Turtoi A, Poupon A, Simony-Lafontaine J, Boissière-Michot F, Pirot N, Bernex F, Jacot W, du Manoir S, Theillet C, Pouget JP, Navarro-Teulon I, Bonnefoy N, Pèlegrin A, Chardès T, Martineau P, Liaudet-Coopman E. Immunotherapy of triple-negative breast cancer with cathepsin D-targeting antibodies J Immunother Cancer. 2019 Feb 4;7(1):29.
3: Stotz S, Bleher D, Kalbacher H, Maurer A. Grassystatin-derived peptides selectively inhibit cathepsin E and have low affinity to cathepsin D Biochem Biophys Res Commun. 2020 Jun 18;527(1):238-241.
4: Proksch E. pH in nature, humans and skin J Dermatol. 2018 Sep;45(9):1044-1052.
5: Gacko M, Minarowska A, Karwowska A, Minarowski Ł. Cathepsin D inhibitors Folia Histochem Cytobiol. 2007;45(4):291-313.
6: Tsukuba T, Okamoto K, Yasuda Y, Morikawa W, Nakanishi H, Yamamoto K. New functional aspects of cathepsin D and cathepsin E Mol Cells. 2000 Dec 31;10(6):601-11.
7: Yamamoto K. Cathepsin E and cathepsin D: biosynthesis, processing and subcellular location Adv Exp Med Biol. 1995;362:223-9.
8: Chlabicz M, Gacko M, Worowska A, Lapiński R. Cathepsin E (EC 3.4.23.34)–a review Folia Histochem Cytobiol. 2011;49(4):547-57.
9: Pal P, Sadhukhan T, Chakraborty S, Sadhukhan S, Biswas A, Das SK, Ray K, Ray J. Role of Apolipoprotein E, Cathepsin D, and Brain-Derived Neurotrophic Factor in Parkinson’s Disease: A Study from Eastern India Neuromolecular Med. 2019 Sep;21(3):287-294.
10: Vidoni C, Follo C, Savino M, Melone MA, Isidoro C. The Role of Cathepsin D in the Pathogenesis of Human Neurodegenerative Disorders Med Res Rev. 2016 Sep;36(5):845-70.

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