Cathepsin B Substrate III Fluorogenic

Description

Cathepsin B Substrate III Fluorogenic
Catalog number: B2014292
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 mg
Molecular Weight or Concentration: 694.61 g/mol
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: −20°C
Keywords: Cathepsin B Substrate III, Fluorogenic, Z-RR-AMC, 2HCl
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Chu DS, Johnson RN, Pun SH. Cathepsin B-sensitive polymers for compartment-specific degradation and nucleic acid release J Control Release. 2012 Feb 10;157(3):445-54.
2: Hulkower KI, Butler CC, Linebaugh BE, Klaus JL, Keppler D, Giranda VL, Sloane BF. Fluorescent microplate assay for cancer cell-associated cathepsin B Eur J Biochem. 2000 Jul;267(13):4165-70.
3: Mahbub Hasan AK, Sato K, Sakakibara K, Ou Z, Iwasaki T, Ueda Y, Fukami Y. Uroplakin III, a novel Src substrate in Xenopus egg rafts, is a target for sperm protease essential for fertilization Dev Biol. 2005 Oct 15;286(2):483-92.
4: Sun J, Wang X, Lin H, Wan L, Chen J, Yang X, Li D, Zhang Y, He X, Wang B, Dong M, Zhong H, Wei C. Shigella escapes lysosomal degradation through inactivation of Rab31 by IpaH4.5 J Med Microbiol. 2021 Jul;70(7).
5: Ben_tez-Bribiesca L, Mart_nez G, Ru_z MT, Gutirrez-Delgado F, Utrera D. Proteinase activity in invasive cancer of the breast. Correlation with tumor progression Arch Med Res. 1995;26 Spec No:S163-8.
6: Brocklehurst K, Kowlessur D, O’Driscoll M, Patel G, Quenby S, Salih E, Templeton W, Thomas EW, Willenbrock F. Substrate-derived two-protonic-state electrophiles as sensitive kinetic specificity probes for cysteine proteinases. Activation of 2-pyridyl disulphides by hydrogen-bonding Biochem J. 1987 May 15;244(1):173-81.
7: Zhang T, Rawson DM, Tosti L, Carnevali O. Cathepsin activities and membrane integrity of zebrafish (Danio rerio) oocytes after freezing to -196 degrees C using controlled slow cooling Cryobiology. 2008 Apr;56(2):138-43.
8: Zheng Y, Lilo S, Mena P, Bliska JB. YopJ-induced caspase-1 activation in Yersinia-infected macrophages: independent of apoptosis, linked to necrosis, dispensable for innate host defense PLoS One. 2012;7(4):e36019.
9: Sakai K, Nii Y, Ueyama A, Kishino Y. Fluorescence demonstration of cathepsin B activity in fractionated alveolar macrophages Cell Mol Biol. 1991;37(3):353-8.
10: Schirmeister T. New peptidic cysteine protease inhibitors derived from the electrophilic alpha-amino acid aziridine-2,3-dicarboxylic acid J Med Chem. 1999 Feb 25;42(4):560-72.

Products Related to Cathepsin B Substrate III Fluorogenic can be found at Substrates