Cartilage Oligomeric Matrix Protein (COMP) Monoclonal Antibody

Product Description

Cartilage Oligomeric Matrix Protein (COMP) Monoclonal Antibody
Catalog number: B2026948
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 ug
Molecular Weight or Concentration: NA
Supplied as: Solution
Storage: −20°C
Keywords: Cartilage Oligomeric Matrix Protein, COMP, Thrombospondin-5, TSP5, EDM1, EPD1, MED, PSACH

References:
1. Geng H, Nandakumar KS, Pramhed A, Aspberg A, Mattsson R, Holmdahl R. Cartilage oligomeric matrix protein specific antibodies are pathogenic. Arthritis Res Ther. 2012;14(4):R191.
2. Li Y, Tong D, Liang P, Lonnblom E, Viljanen J, Xu B, Nandakumar KS, Holmdahl R. Cartilage-binding antibodies initiate joint inflammation and promote chronic erosive arthritis. Arthritis Res Ther. 2020;22(1):120.
3. Ge C, Xu B, Liang P, Lonnblom E, Lundström SL, Zubarev RA, Viljanen J, Altmann F, Larsson A, Klareskog L, Holmdahl R. Antibodies to Cartilage Oligomeric Matrix Protein Are Pathogenic in Mice and May Be Clinically Relevant in Rheumatoid Arthritis. Arthritis Rheumatol. 2022;74(5):780-791.
4. Gouttenoire J, Valcourt U, Ronziere MC, Herbage D, Mallein-Gerin F. Modulating the expression of cartilage oligomeric matrix protein (COMP) by factors that control chondrogenesis. Matrix Biol. 2004;23(6):383-393.
5. Happonen KE, Saxne T, Aspberg A, Morgelin M, Heinegard D, Blom AM. Regulation of complement by cartilage oligomeric matrix protein allows for a novel molecular diagnostic principle in rheumatoid arthritis. Arthritis Rheum. 2010;62(12):3552-3561.
6. Heinegard D, Saxne T. The role of the cartilage matrix in osteoarthritis. Nat Rev Rheumatol. 2011;7(1):50-56.
7. Newton G, Weremowicz S, Morton CC, Copeland NG, Gilbert DJ, Jenkins NA, Lawler J. Characterization of the human and mouse cartilage oligomeric matrix protein genes. Genomics. 1994;24(3):435-439.
8. Sodersten F, Ekman S, Eloranta ML, Heinegard D, Dudhia J, Hultenby K. Ultrastructural immunolocalization of cartilage oligomeric matrix protein (COMP) in relation to collagen fibrils in the equine tendon. Matrix Biol. 2005;24(5):376-385.
9. Tseng S, Reddi AH, Di Cesare PE. Cartilage oligomeric matrix protein (COMP): a biomarker of arthritis. Biomarkers. 2009;14(2):61-76.
10. Zaucke F, Dinser R, Maurer P, Paulsson M. Cartilage oligomeric matrix protein (COMP): structure, glycosylation and genetics. Biochem Soc Trans. 2001;29(Pt 6):830-835.
Cartilage Oligomeric Matrix Protein (COMP) , Monoclonal Antibody (Clone 15A11)

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