C-Telopeptide Type I Collagen Polyclonal Antibody

Product Description

C-Telopeptide Type I Collagen Polyclonal Antibody
Catalog number: B2010382
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 ug
Molecular Weight or Concentration: 150 kDa
Supplied as: Liquid
Appearance: Clear Solution
Applications: a rabbit polyclonal antibody specific to the cross-linked C-Telopeptide of Type I Collagen (CTXI). This antibody has been purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography.
Storage: -20C
Keywords: CTXI antibody, C-telopeptide antibody
Grade: Biotechnology grade. All solid components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Chubb SA. Measurement of C-terminal telopeptide of type I collagen (CTX) in
serum. Clin Biochem. 2012 Aug;45(12):928-35.

2: Malone JP, Veis A. Heterotrimeric type I collagen C-telopeptide conformation
as docked to its helix receptor. Biochemistry. 2004 Dec 14;43(49):15358-66.

3: Łęgosz P, Pulik Ł, Stępiński P, Janowicz J, Wirkowska A, Kotela A, Sarzyńska
S, Małdyk P. The Use of Type I_Collagen Cross-Linked C-Telopeptide (CTX-1) as a
Biomarker Associated with the Formation of Periprosthetic Ossifications
Following Total Hip Joint Arthroplasty. Ann Clin Lab Sci. 2018
Mar;48(2):183-190.

4: Kalamajski S, Liu C, Tillgren V, Rubin K, Oldberg Å, Rai J, Weis M, Eyre DR.
Increased C-telopeptide cross-linking of tendon type I collagen in fibromodulin-
deficient mice. J Biol Chem. 2014 Jul 4;289(27):18873-9.

5: Garnero P, Schott AM, Prockop D, Chevrel G. Bone turnover and type_I_collagen
C-telopeptide isomerization in adult osteogenesis imperfecta: associations with
collagen gene mutations. Bone. 2009 Mar;44(3):461-6.

6: McNulty M, Mahmud A, Spiers P, Feely J. Collagen type-I degradation is
related to arterial stiffness in hypertensive and normotensive subjects. J Hum
Hypertens. 2006 Nov;20(11):867-73.
7: Selistre LFA, Gonçalves GH, Vasilceac FA, Serrão PRMDS, Nakagawa TH, Petrella
M, Jones RK, Mattiello SM. The relationship between urinary C-Telopeptide
fragments of type II collagen, knee joint load, pain, and physical function in
individuals with medial knee osteoarthritis. Braz J Phys Ther. 2021 Jan-
Feb;25(1):62-69.

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