Brain-Derived Neurotrophic Factor (BDNF)

Description

Brain-Derived Neurotrophic Factor (BDNF)
Catalog number: B2010332
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 10 ug
pH: 7.4 upon reconstitution
Supplied as: Lyophilized Powder
Appearance: Powder
Applications: highly pure Brain-Derived Neurotrophic Factor (BDNF) expressed in E. coli. This protein acts as a neurotrophin that binds to the tropomyosin-related receptor kinase B (TrkB) receptor and regulates neurodevelopmental processes.
Storage: -20C
Keywords: rHuBDNF/Brain-derived neurotrophic factor; Abrineurin
Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Di Carlo P, Punzi G, Ursini G. Brain-derived neurotrophic factor and
schizophrenia. Psychiatr Genet. 2019 Oct;29(5):200-210.

2: Lima Giacobbo B, Doorduin J, Klein HC, Dierckx RAJO, Bromberg E, de Vries
EFJ. Brain-Derived Neurotrophic Factor in Brain Disorders: Focus on
Neuroinflammation. Mol Neurobiol. 2019 May;56(5):3295-3312.

3: Notaras M, van den Buuse M. Brain-Derived Neurotrophic Factor (BDNF): Novel
Insights into Regulation and Genetic Variation. Neuroscientist. 2019
Oct;25(5):434-454.

4: Zuccato C, Cattaneo E. Brain-derived neurotrophic factor in neurodegenerative
diseases. Nat Rev Neurol. 2009 Jun;5(6):311-22.

5: Daly C, Ward R, Reynolds AL, Galvin O, Collery RF, Kennedy BN. Brain-Derived
Neurotrophic Factor as a Treatment Option for Retinal Degeneration. Adv Exp Med
Biol. 2018;1074:465-471.

6: Sonal A, Raghavan V. Brain derived neurotrophic factor (BDNF) and suicidal
behavior: A review of studies from Asian countries. Asian J Psychiatr. 2018
Mar;33:128-132.

7: Jablochkova A, Bäckryd E, Kosek E, Mannerkorpi K, Ernberg M, Gerdle B,
Ghafouri B. Unaltered low nerve growth factor and high brain-derived
neurotrophic factor levels in plasma from patients with fibromyalgia after a
15-week progressive resistance exercise. J Rehabil Med. 2019 Oct
29;51(10):779-787.

8: Xu B, Xie X. Neurotrophic factor control of satiety and body weight. Nat Rev
Neurosci. 2016 May;17(5):282-92.
9: Björkholm C, Monteggia LM. BDNF – a key transducer of antidepressant effects.
Neuropharmacology. 2016 Mar;102:72-9.

Products Related to Brain-Derived Neurotrophic Factor (BDNF) : Proteins