Apo Lactoferrin from Human Breast Milk

Product Description

Apo Lactoferrin from Human Breast Milk
Catalog number: B2012199
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 mg
Molecular Weight or Concentration: 78 kDa
Supplied as: Lyophilized
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: Apo-Lactoferrin, apolactoferrin, apo-lf
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Reyes-López M, Ramírez-Rico G, Serrano-Luna J, de la Garza M. Activity of Apo-Lactoferrin on Pathogenic Protozoa Pharmaceutics. 2022 Aug 15;14(8):1702.
2: Zhang Z, Lu M, Chen C, Tong X, Li Y, Yang K, Lv H, Xu J, Qin L. Holo-lactoferrin: the link between ferroptosis and radiotherapy in triple-negative breast cancer Theranostics. 2021 Jan 1;11(7):3167-3182.
3: Ramírez-Rico G, Martinez-Castillo M, Avalos-Gómez C, de la Garza M. Bovine apo-lactoferrin affects the secretion of proteases in Mannheimia haemolytica A2 Access Microbiol. 2021 Oct 25;3(10):000269.
4: Zakharova ET, Kostevich VA, Sokolov AV, Vasilyev VB. Human apo-lactoferrin as a physiological mimetic of hypoxia stabilizes hypoxia-inducible factor-1 alpha Biometals. 2012 Dec;25(6):1247-59.
5: Avalos-Gómez C, Reyes-López M, Ramírez-Rico G, Díaz-Aparicio E, Zenteno E, González-Ruiz C, de la Garza M. Effect of apo-lactoferrin on leukotoxin and outer membrane vesicles of Mannheimia haemolytica A2 Vet Res. 2020 Mar 5;51(1):36.
6: Akilo OD, Kumar P, Choonara YE, Pradeep P, du Toit LC, Pillay V. Hypothesis: apo-lactoferrin-Galantamine Proteo-alkaloid Conjugate for Alzheimer’s disease Intervention J Cell Mol Med. 2018 Mar;22(3):1957-1963.
7: Luzi C, Brisdelli F, Iorio R, Bozzi A, Carnicelli V, Di Giulio A, Lizzi AR. Apoptotic effects of bovine apo-lactoferrin on HeLa tumor cells Cell Biochem Funct. 2017 Jan;35(1):33-41.
8: Mikulic N, Uyoga MA, Mwasi E, Stoffel NU, Zeder C, Karanja S, Zimmermann MB. Iron Absorption is Greater from Apo-Lactoferrin and is Similar Between Holo-Lactoferrin and Ferrous Sulfate: Stable Iron Isotope Studies in Kenyan Infants J Nutr. 2020 Dec 10;150(12):3200-3207.
9: Liu H, Wu H, Zhu N, Xu Z, Wang Y, Qu Y, Wang J. Lactoferrin protects against iron dysregulation, oxidative stress, and apoptosis in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinson’s disease in mice J Neurochem. 2020 Feb;152(3):397-415.
10: Jiang R, Lönnerdal B. Apo- and holo-lactoferrin stimulate proliferation of mouse crypt cells but through different cellular signaling pathways Int J Biochem Cell Biol. 2012 Jan;44(1):91-100.

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