Anti-GQ1b Monoclonal Antibody

Product Description

Anti-GQ1b Monoclonal Antibody
Catalog number: B2015027
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 ug
Molecular Weight or Concentration: N/A
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20° C
Keywords: Anti-GQ1b Monoclonal Antibody
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Nakatani Y, Murata M, Shibata K, Nagaoka T, Utsunomiya I, Usuki S, Miyatake T, Hoshi K, Taguchi K. IgM anti-GQ1b monoclonal antibody inhibits voltage-dependent calcium current in cerebellar granule cells Exp Neurol. 2009 Sep;219(1):74-80.
2: Bourque PR, Chardon JW, Massie R. Autoimmune peripheral neuropathies Clin Chim Acta. 2015 Sep 20;449:37-42.
3: Willison HJ, O’Hanlon G, Paterson G, O’Leary CP, Veitch J, Wilson G, Roberts M, Tang T, Vincent A. Mechanisms of action of anti-GM1 and anti-GQ1b ganglioside antibodies in Guillain-Barré syndrome J Infect Dis. 1997 Dec;176 Suppl 2:S144-9.
4: Kusunoki S, Chiba A. [Fisher syndrome and anti-GQ1b antibody] Nihon Rinsho. 1994 Nov;52(11):2959-64.
5: Kusunoki S, Chiba A, Kanazawa I. Anti-GQ1b IgG antibody is associated with ataxia as well as ophthalmoplegia Muscle Nerve. 1999 Aug;22(8):1071-4.
6: Chiba A, Kusunoki S, Obata H, Machinami R, Kanazawa I. Serum anti-GQ1b IgG antibody is associated with ophthalmoplegia in Miller Fisher syndrome and Guillain-Barré syndrome: clinical and immunohistochemical studies Neurology. 1993 Oct;43(10):1911-7.
7: Bullens RW, O’Hanlon GM, Goodyear CS, Molenaar PC, Conner J, Willison HJ, Plomp JJ. Anti-GQ1b antibodies and evoked acetylcholine release at mouse motor endplates Muscle Nerve. 2000 Jul;23(7):1035-43.
8: Buchwald B, Ahangari R, Toyka KV. Differential blocking effects of the monoclonal anti-GQ1b IgM antibody and alpha-latrotoxin in the absence of complement at the mouse neuromuscular junction Neurosci Lett. 2002 Dec 6;334(1):25-8.
9: Halstead SK, Zitman FM, Humphreys PD, Greenshields K, Verschuuren JJ, Jacobs BC, Rother RP, Plomp JJ, Willison HJ. Eculizumab prevents anti-ganglioside antibody-mediated neuropathy in a murine model Brain. 2008 May;131(Pt 5):1197-208.
10: Willison HJ, Townson K, Veitch J, Boffey J, Isaacs N, Andersen SM, Zhang P, Ling CC, Bundle DR. Synthetic disialylgalactose immunoadsorbents deplete anti-GQ1b antibodies from autoimmune neuropathy sera Brain. 2004 Mar;127(Pt 3):680-91.

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