Alpha-2 Antiplasmin (Highly Pure)

Description

Alpha-2 Antiplasmin (Highly Pure)
Catalog number: B2012251
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 ug
Molecular Weight or Concentration: 65 kDa
Supplied as: Lyophilized
Applications: molecular tool for various biochemical applications
Storage: -20C
Keywords: A2AP, alpha 2-antiplasmin, Plasmin Inhibitor
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Matrane W, Bencharef H, Oukkache B. Congenital Alpha-2 Antiplasmin Deficiency: a Literature Survey and Analysis of 123 Cases Clin Lab. 2020 Dec 1;66(12).
2: Mohammed BAB. Alpha 2-antiplasmin deficiency in a Sudanese child: a case report J Med Case Rep. 2021 May 7;15(1):238.
3: Lee KN, Lee CS, Tae WC, Jackson KW, Christiansen VJ, McKee PA. Crosslinking of alpha 2-antiplasmin to fibrin Ann N Y Acad Sci. 2001;936:335-9.
4: Rijken DC, Groeneveld E, Kluft C, Nieuwenhuis HK. Alpha 2-antiplasmin Enschede is not an inhibitor, but a substrate, of plasmin Biochem J. 1988 Oct 15;255(2):609-15.
5: Stettler GR, Moore EE, Huebner BR, Nunns GR, Moore HB, Coleman JR, Kelher M, Banerjee A, Silliman CC. 28-day thawed plasma maintains α(2) -antiplasmin levels and inhibits tPA-induced fibrinolysis Vox Sang. 2021 Feb;116(2):181-189.
6: Plow EF, Miles LA, Collen D. Platelet alpha 2-antiplasmin Methods Enzymol. 1989;169:296-300.
7: Longstaff C, Locke M. Increased urokinase and consumption of α(2) -antiplasmin as an explanation for the loss of benefit of tranexamic acid after treatment delay J Thromb Haemost. 2019 Jan;17(1):195-205.
8: Wzorek J, Karpiński M, Wypasek E, Michalski M, Szczudlik A, Malinowski KP, Undas A. Alpha-2-antiplasmin Arg407Lys polymorphism and cryptogenic ischemic cerebrovascular events: Association with neurological deficit Neurol Neurochir Pol. 2018 May-Jun;52(3):352-358.
9: Tsurupa G, Yakovlev S, McKee P, Medved L. Noncovalent interaction of alpha(2)-antiplasmin with fibrin(ogen): localization of alpha(2)-antiplasmin-binding sites Biochemistry. 2010 Sep 7;49(35):7643-51.
10: Holmes WE, Lijnen HR, Nelles L, Kluft C, Nieuwenhuis HK, Rijken DC, Collen D. Alpha 2-antiplasmin Enschede: alanine insertion and abolition of plasmin inhibitory activity Science. 1987 Oct 9;238(4824):209-11.

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