Adenosine Deaminase

Description

Adenosine Deaminase
Catalog number: B2013727
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 ku
Molecular Weight or Concentration: 3 U/mg protein
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: Adenosine Deaminase
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Bradford KL, Moretti FA, Carbonaro-Sarracino DA, Gaspar HB, Kohn DB. Adenosine Deaminase (ADA)-Deficient Severe Combined Immune Deficiency (SCID): Molecular Pathogenesis and Clinical Manifestations J Clin Immunol. 2017 Oct;37(7):626-637.
2: Gao ZW, Wang X, Zhang HZ, Lin F, Liu C, Dong K. The roles of adenosine deaminase in autoimmune diseases Autoimmun Rev. 2021 Jan;20(1):102709.
3: Kohn DB, Hershfield MS, Puck JM, Aiuti A, Blincoe A, Gaspar HB, Notarangelo LD, Grunebaum E. Consensus approach for the management of severe combined immune deficiency caused by adenosine_deaminase deficiency J Allergy Clin Immunol. 2019 Mar;143(3):852-863.
4: Corts A, Gracia E, Moreno E, Mallol J, Llu_s C, Canela EI, Casad_ V. Moonlighting adenosine_deaminase: a target protein for drug development Med Res Rev. 2015 Jan;35(1):85-125.
5: Davis FF. PEG-adenosine deaminase and PEG-asparaginase Adv Exp Med Biol. 2003;519:51-8.
6: Maiuolo J, Oppedisano F, Gratteri S, Muscoli C, Mollace V. Regulation of uric acid metabolism and excretion Int J Cardiol. 2016 Jun 15;213:8-14.
7: Schnappauf O, Ombrello AK, Kastner DL. Deficiency of adenosine_deaminase 2: Is it an elephant after all? J Allergy Clin Immunol. 2020 Jun;145(6):1560-1561.
8: Gao ZW, Wang X, Lin F, Dong K. Total adenosine_deaminase highly correlated with adenosine_deaminase 2 activity in serum Ann Rheum Dis. 2022 Feb;81(2):e30.
9: Hirschhorn R, Ratech H. Isozymes of adenosine_deaminase Isozymes Curr Top Biol Med Res. 1980;4:131-57.
10: Cristalli G, Costanzi S, Lambertucci C, Lupidi G, Vittori S, Volpini R, Camaioni E. Adenosine deaminase: functional implications and different classes of inhibitors Med Res Rev. 2001 Mar;21(2):105-28.

Products Related to Adenosine Deaminase can be found at Enzymes