ACTH (Human, 1-24)

Product Description

ACTH (Human, 1-24)
Catalog number: MDP0477
CAS Number: 37642-65-2
Sequence: Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro
Amount: 500 ug
Molecular Weight: 2933.2 g/mol
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: -20 °C
WARNING: For in vitro Research Use Only. NOT for use on humans or animals.
Grade: Biotechnology grade. All products are highly pure.

References:
1: Liang L, Angleson JK, Dores RM. Using the human melanocortin-2 receptor as a model for analyzing hormone/receptor interactions between a mammalian MC2 receptor and ACTH(1-24) Gen Comp Endocrinol. 2013 Jan 15;181:203-10.
2: Hughes RA, Brassington R, Gunn AA, van Doorn PA. Corticosteroids for Guillain-Barré syndrome Cochrane Database Syst Rev. 2016 Oct 24;10(10):CD001446.
3: Bertolini A, Noera G. ACTH 1-24 and other melanocortins for COVID-19 treatment Shock. 2020 Nov;54(5):701-702.
4: Genedani S, Bernardi M, Baldini MG, Bertolini A. ACTH(1-24) stimulates the migration of human monocytes in vitro Peptides. 1990 Nov-Dec;11(6):1305-7.
5: Poola N, Due B, Wright D, Brooks LR, Zaman F. Pharmacokinetics and Pharmacodynamics of Repository Corticotropin Injection Compared With Synthetic ACTH(1-24) Depot and Methylprednisolone in Healthy Subjects Clin Pharmacol Drug Dev. 2022 Apr;11(4):502-515.
6: O’Callaghan FJ, Edwards SW, Alber FD, Hancock E, Johnson AL, Kennedy CR, Likeman M, Lux AL, Mackay M, Mallick AA, Newton RW, Nolan M, Pressler R, Rating D, Schmitt B, Verity CM, Osborne JP; participating investigators. Safety and effectiveness of hormonal treatment versus hormonal treatment with vigabatrin for infantile spasms (ICISS): a randomised, multicentre, open-label trial Lancet Neurol. 2017 Jan;16(1):33-42.
7: Raff H, Findling JW, Wong J. Short loop adrenocorticotropin (ACTH) feedback after ACTH-(1-24) injection in man is an artifact of the immunoradiometric assay J Clin Endocrinol Metab. 1989 Sep;69(3):678-80.
8: Cavagnini F, Fossati R. ACTH 1-17 and pituitary-adrenal function in human Ric Clin Lab. 1984 Apr-Jun;14(2):159-65.
9: Yoshida-Hiroi M, Tsuchida Y, Yoshino G, Hiroi N. Intranasal administration of ACTH(1-24) stimulates catecholamine secretion Horm Metab Res. 2005 Aug;37(8):489-93.
10: Kokubo M, Asai K, Yamamoto N, Aoyama M, Morikawa M, Togari H, Wada Y, Kato T. ACTH(1-24) down-regulates expression of ciliary neurotrophic factor mRNA in cultured rat astrocyte Pediatr Res. 2002 Dec;52(6):950-7.

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