Name: 6-Monodeoxy-6-monoiodo-beta-cyclodextrin
Brand: Molecular Depot
SKU: B2027369
Price: 895 USD
Availability: InStock
Rating: 5 (2 reviews)

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6-Monodeoxy-6-monoiodo-beta-cyclodextrin

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Catalog Number: B2027369 (100 mg)
6-Monodeoxy-6-monoiodo-beta-cyclodextrin is a selectively functionalized cyclodextrin derivative where a single primary hydroxyl group is replaced with an iodine atom. This halogenated derivative serves as a versatile intermediate in organic synthesis, enabling nucleophilic substitution reactions to introduce diverse functional groups or ligands onto the primary rim. It retains the characteristic hydrophobic cavity of beta-cyclodextrin, allowing for host-guest inclusion complexation in bioconjugation research. Custom bulk amounts of this product are available upon request.

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SKU: B2027369 Category: Powder Tag: MD 1000

Product Description

5/5 - (2 votes)

6-Monodeoxy-6-monoiodo-beta-cyclodextrin
Catalog number: B2027369
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 mg
Molecular Weight or Concentration: 1244.9
Supplied as: Chemicals
Storage: 2-8 ˚C
Keywords: 6-Iodo-6-deoxy-beta-cyclodextrin, 6-I-β-CD, 6-Monodeoxy-6-monoiodo-β-cyclodextrin, Mono-6-deoxy-6-iodo-beta-cyclodextrin

References:
1. Gadelle, A., & Defaye, J. (1991). Selective conversion of beta-cyclodextrin into 6-monodeoxy-6-monoiodo-beta-cyclodextrin. Angewandte Chemie International Edition in English, 30(1), 78-80.
2. Ashton, P. R., Ellwood, P., Staton, I., & Stoddart, J. F. (1991). Synthesis and characterization of 6-deoxy-6-iodo-beta-cyclodextrin derivatives. Journal of the Chemical Society, Chemical Communications, (8), 532-534.
3. Jicsinszky, L., & Iványi, R. (2001). Halogenation reactions of cyclodextrins under green chemical conditions. Journal of Inclusion Phenomena and Macrocyclic Chemistry, 40(4), 283-288.
4. Khan, A. R., Forgo, P., Stine, K. J., & D’Souza, V. T. (1998). Methods for selective modification of cyclodextrins. Chemical Reviews, 98(5), 1977-1996.
5. Mellet, C. O., Defaye, J., & Fernández, J. M. G. (2002). Synthesis and properties of mono- and multivalent cyclodextrin derivatives. Advanced Drug Delivery Reviews, 54(2), 263-285.
6. Guillo, F., Hamelin, B., Jullien, L., Canceill, J., & Lehn, J. M. (1995). Regiospecific functionalization of cyclodextrins at the primary face. Bulletin de la Société Chimique de France, 132(8), 857-866.
7. Rong, D., & D’Souza, V. T. (1990). A convenient method for functionalization of primary mono-hydroxyl group of cyclodextrins. Tetrahedron Letters, 31(30), 4275-4278.
8. Yoon, J., Hong, S., Martin, K. A., & Czarnik, A. W. (1995). A general synthetic route to mono-functionalized cyclodextrins. Journal of Organic Chemistry, 60(9), 2792-2795.
9. Tang, W., & Ng, S. C. (2008). Functionalized cyclodextrins for chiral separations by liquid chromatography and capillary electrophoresis. Journal of Chromatography A, 1184(1-2), 470-486.
10. Szejtli, J. (1998). Introduction and general overview of cyclodextrin chemistry. Chemical Reviews, 98(5), 1743-1754.
6-Monodeoxy-6-monoiodo-beta-cyclodextrin

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