5-Methoxy-DL-tryptophan (Highly Pure)

Product Description

5-Methoxy-DL-tryptophan (Highly Pure)
Catalog number: B2016251
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 mg
Molecular Weight or Concentration: 234.26 g/mol
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: -20°C
Keywords: H-5-MeO-DL-Trp-OH
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Setyaningsih W, Saputro IE, Carrera CA, Palma M, Barroso CG. Multiresponse optimization of a UPLC method for the simultaneous determination of tryptophan and 15 tryptophan-derived compounds using a Box-Behnken design with a desirability function Food Chem. 2017 Jun 15;225:1-9.
2: Ikeda A, Sekiguchi K, Fujita K, Yamadera H, Koga Y. 5-methoxy-N,N-diisopropyltryptamine-induced flashbacks Am J Psychiatry. 2005 Apr;162(4):815.
3: Chai WM, Yu ZY, Lin MZ, Wei QM, Song S. 5-Methoxy-2-mercaptobenzimidazole as an efficient inhibitor on tyrosinase: Inhibitory activity and mechanism J Biosci Bioeng. 2021 Apr;131(4):356-363.
4: Abiero A, Botanas CJ, Sayson LV, Custodio RJ, de la Peña JB, Kim M, Lee HJ, Seo JW, Ryu IS, Chang CM, Yang JS, Lee YS, Jang CG, Kim HJ, Cheong JH. 5-Methoxy-α-methyltryptamine (5-MeO-AMT), a tryptamine derivative, induces head-twitch responses in mice through the activation of serotonin receptor 2a in the prefrontal cortex Behav Brain Res. 2019 Feb 1;359:828-835.
5: Fun HK, Yeap CS, Chidan Kumar CS, Yathirajan HS, Siddegowda MS. 4,6-Dichloro-5-methoxy-pyrimidine Acta Crystallogr Sect E Struct Rep Online. 2010 Jan 20;66(Pt 2):o408.
6: Chen DQ, Cao G, Chen H, Argyopoulos CP, Yu H, Su W, Chen L, Samuels DC, Zhuang S, Bayliss GP, Zhao S, Yu XY, Vaziri ND, Wang M, Liu D, Mao JR, Ma SX, Zhao J, Zhang Y, Shang YQ, Kang H, Ye F, Cheng XH, Li XR, Zhang L, Meng MX, Guo Y, Zhao YY. Identification of serum metabolites associating with chronic kidney disease progression and anti-fibrotic effect of 5-methoxytryptophan Nat Commun. 2019 Apr 1;10(1):1476.
7: Zhao TL, Qi Y, Wang YF, Wang Y, Liang H, Pu YB. 5-methoxytryptophan induced apoptosis and PI3K/Akt/FoxO3a phosphorylation in colorectal cancer World J Gastroenterol. 2023 Dec 21;29(47):6148-6160.
8: Cho JY, Cowling RT. 5-Methoxytryptophan: A game changer in the management of post-myocardial infarction? J Mol Cell Cardiol. 2021 Nov;160:71-72.
9: Wu KK. Control of Tissue Fibrosis by 5-Methoxytryptophan, an Innate Anti-Inflammatory Metabolite Front Pharmacol. 2021 Nov 11;12:759199.
10: Maassen S, Warner H, Ioannidis M, Jansma J, Markus H, El Aidy S, Chiara MD, Chiara JL, Maierhofer L, Weavers H, van den Bogaart G. Mitochondrial interaction of fibrosis-protective 5-methoxy tryptophan enhances collagen uptake by macrophages Free Radic Biol Med. 2022 Aug 1;188:287-297.

Products Related to 5-Methoxy-DL-tryptophan (Highly Pure) can be found at Proteins