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360 MMP FRET Substrate V

Original price was: $1,595.00.Current price is: $795.00.

Catalog Number: B2019441 (1 mg)
360 MMP FRET Substrate V is a biochemical substrate used in fluorescence resonance energy transfer (FRET) assays to study matrix metalloproteinases (MMPs). It emits fluorescence when cleaved by specific MMPs, allowing real-time monitoring of MMP activity. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Product Description

5/5 - (1 vote)

360 MMP FRET Substrate V
Catalog number: B2019441
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: 1164.3
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: -20°C
Keywords: Dnp-RPLALWRS
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: van Ginkel J, Filius M, Szczepaniak M, Tulinski P, Meyer AS, Joo C. Single-molecule peptide fingerprinting Proc Natl Acad Sci U S A. 2018 Mar 27;115(13):3338-3343.
2: Arutyunova E, Strisovsky K, Lemieux MJ. Activity Assays for Rhomboid Proteases Methods Enzymol. 2017;584:395-437.
3: Ødum AS, Olesen K, Østergaard S, Thim L, Nørby I, Meldal M. Substrate Specificity Profiling of Peptidyl-Lys Metallopeptidase of Armillaria mellea by FRET Based Peptide Library Protein Pept Lett. 2015;22(6):514-24.
4: Lafontaine DA, Norman DG, Lilley DM. The global structure of the VS ribozyme EMBO J. 2002 May 15;21(10):2461-71.
5: Peter MF, Gebhardt C, Glaenzer J, Schneberger N, de Boer M, Thomas GH, Cordes T, Hagelueken G. Triggering Closure of a Sialic Acid TRAP Transporter Substrate Binding Protein through Binding of Natural or Artificial Substrates J Mol Biol. 2021 Feb 5;433(3):166756.
6: Ciubotaru M, Surleac MD, Metskas LA, Koo P, Rhoades E, Petrescu AJ, Schatz DG. The architecture of the 12RSS in V(D)J recombination signal and synaptic complexes Nucleic Acids Res. 2015 Jan;43(2):917-31.
7: Haak W, Jagt JZ, de Meij TGJ, Bikker FJ, Brand HS, de Boer NKH, Kaman WE. Fecal proteolytic profiling of pediatric inflammatory bowel disease: A pilot study FASEB J. 2024 May 15;38(9):e23627.
8: Stojanovski BM, Di Cera E. Monitoring prothrombin activation in plasma through loss of Förster resonance energy transfer J Thromb Haemost. 2023 Jul;21(7):1769-1778.
9: Jensen SB, Thodberg S, Parween S, Moses ME, Hansen CC, Thomsen J, Sletfjerding MB, Knudsen C, Del Giudice R, Lund PM, Castaño PR, Bustamante YG, Velazquez MNR, Jørgensen FS, Pandey AV, Laursen T, Møller BL, Hatzakis NS. Biased cytochrome P450-mediated metabolism via small-molecule ligands binding P450 oxidoreductase Nat Commun. 2021 Apr 15;12(1):2260.
10: Chiou WC, Chen JC, Chen YT, Yang JM, Hwang LH, Lyu YS, Yang HY, Huang C. The inhibitory effects of PGG and EGCG against the SARS-CoV-2 3C-like protease Biochem Biophys Res Commun. 2022 Feb 5;591:130-136.

Products Related to 360 MMP FRET Substrate V can be found at Substrates

Additional Information

Weight 0.15 oz
Dimensions 2 × 0.5 × 0.5 in
5/5 - (1 vote)

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