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360 MMP FRET Substrate IV

Original price was: $1,595.00.Current price is: $795.00.

Catalog Number: B2019491 (5 mg)
360 MMP FRET Substrate IV is a biochemical reagent used in research to study matrix metalloproteinases (MMPs). It emits a fluorescent signal when cleaved by specific MMPs, allowing measurement of interactions between molecules. This substrate is useful for studying MMP activity in biological samples and can be used in high-throughput screening assays. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Product Description

5/5 - (1 vote)

360 MMP FRET Substrate IV
Catalog number: B2019491
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 mg
Molecular Weight or Concentration: 1152.3
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: -20°C
Keywords: Dnp-PYAYWMR
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Vos SM, Lee I, Berger JM. Distinct regions of the Escherichia coli ParC C-terminal domain are required for substrate discrimination by topoisomerase IV J Mol Biol. 2013 Sep 9;425(17):3029-45.
2: Milligan G, Wilson S, López-Gimenez JF. The specificity and molecular basis of alpha1-adrenoceptor and CXCR chemokine receptor dimerization J Mol Neurosci. 2005;26(2-3):161-8.
3: Chopra A. Fibroblast activation protein α–specific, near-infrared peptide probe (KGPGPNQC) linked to Cy5.5 and a quencher dye, QSY21 2012 Oct 31 [updated 2012 Nov 21]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013.
4: Bourdès A, Rudder S, East AK, Poole PS. Mining the Sinorhizobium meliloti transportome to develop FRET biosensors for sugars, dicarboxylates and cyclic polyols PLoS One. 2012;7(9):e43578.
5: Newton P, Latomanski EA, Newton HJ. Applying Fluorescence Resonance Energy Transfer (FRET) to Examine Effector Translocation Efficiency by Coxiella burnetii during siRNA Silencing J Vis Exp. 2016 Jul 6;(113):54210.
6: Hu X, Compton JR, Legler PM. Analysis of Group IV Viral SSHHPS Using In Vitro and In Silico Methods J Vis Exp. 2019 Dec 21;(154).
7: Marcink TC, Simoncic JA, An B, Knapinska AM, Fulcher YG, Akkaladevi N, Fields GB, Van Doren SR. MT1-MMP Binds Membranes by Opposite Tips of Its β Propeller to Position It for Pericellular Proteolysis Structure. 2019 Feb 5;27(2):281-292.e6.
8: Lee J, Samson AAS, Song JM. Inkjet printing-based β-secretase fluorescence resonance energy transfer (FRET) assay for screening of potential β-secretase inhibitors of Alzheimer’s disease Anal Chim Acta. 2018 Aug 31;1022:89-95.
9: De Simone A, Seidl C, Santos CA, Andrisano V. Liquid chromatographic enzymatic studies with on-line Beta-secretase immobilized enzyme reactor and 4-(4-dimethylaminophenylazo) benzoic acid/5-[(2-aminoethyl) amino] naphthalene-1-sulfonic acid peptide as fluorogenic substrate J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Mar 15;953-954:108-14.
10: De Simone A, Seidl C, Santos CA, Andrisano V. Reprint of: Liquid chromatographic enzymatic studies with on-line Beta-secretase immobilized enzyme reactor and 4-(4-dimethylaminophenylazo) benzoic acid/5-[(2-aminoethyl) amino] naphthalene-1-sulfonic acid peptide as fluorogenic substrate J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Oct 1;968:94-100.

Products Related to 360 MMP FRET Substrate IV can be found at Substrates

Additional Information

Weight 0.15 oz
Dimensions 2 × 0.5 × 0.5 in
5/5 - (1 vote)

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