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3,3′,5′-Triiodo-L-thyronine

$795.00

Catalog Number: B2010546 (10 mg)
3,3′,5′-Triiodo-L-thyronine is a highly pure (> 95.0% by HPLC) thyroid hormone analog. This product has been used as molecular tool for various research experiments. It has also been used in a wide array of other biochemical and immunological applications. Custom bulk amounts of this product are available upon request.

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SKU: B2010546 Categories: ,

Description

3,3′,5′-Triiodo-L-thyronine
Catalog number: B2010546
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 mg
Molecular Weight or Concentration: 650.97 g/mol
Supplied as: Powder
Applications: molecular tool for various research experiments
Storage: −20°C
Keywords: Reverse T3, rT(3)
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Grymuła K, Paczkowska E, Dziedziejko V, Baśkiewicz-Masiuk M, Kawa M, Baumert
B, Celewicz Z, Gawrych E, Machaliński B. The influence of 3,3′,5-triiodo-L-
thyronine on human haematopoiesis. Cell Prolif. 2007 Jun;40(3):302-15.

2: Cahnmann HJ, Gonçalves E, Ito Y, Fales HM, Sokoloski EA. Synthesis and
characterization of N-bromoacetyl-3,3′,5-triiodo-L-thyronine. J Chromatogr. 1991
Jan 18;538(1):165-75.

3: Kitagawa S, Obata T, Hasumura S, Pastan I, Cheng SY. A cellular
3,3′,5-triiodo-L-thyronine binding protein from a human carcinoma cell line.
Purification and characterization. J Biol Chem. 1987 Mar 15;262(8):3903-8.

4: Cheng SY, Ransom SC, McPhie P, Bhat MK, Mixson AJ, Wintraub BD. Analysis of
the binding of 3,3′,5-triiodo-L-thyronine and its analogues to mutant human beta
1 thyroid hormone receptors: a model of the hormone binding site. Biochemistry.
1994 Apr 12;33(14):4319-26.

5: Groeneweg S, Peeters RP, Visser TJ, Visser WE. Triiodothyroacetic acid in
health and disease. J Endocrinol. 2017 Aug;234(2):R99-R121.

6: Hoffenberg R. Triiodothyronine. Clin Endocrinol (Oxf). 1973 Jan;2(1):75-87.

7: Richards K, Rijntjes E, Rathmann D, Köhrle J. Avoiding the pitfalls when
quantifying thyroid hormones and their metabolites using mass spectrometric
methods: The role of quality assurance. Mol Cell Endocrinol. 2017 Dec
15;458:44-56.

8: PITTMAN JA, BROWN RW, REGISTER HB Jr. Biological activity of 3,3′,5′-triiodo-
DL-thyronine. Endocrinology. 1962 Jan;70:79-83.

9: Sar P, Rath B, Subudhi U, Chainy GB, Supakar PC. Alterations in expression of
senescence marker protein-30 gene by 3,3′,5-triiodo-L-thyronine (T3). Mol Cell
Biochem. 2007 Sep;303(1-2):239-42.
10: Rodríguez-Molinero A, Hercbergs A, Sarrias M, Yuste A. Plasma
3,3′,5-Triiodo-L-thyronine [T3] level mirrors changes in tumor markers in two
cases of metastatic cancer of the breast and pancreas treated with exogenous
L-T3. Cancer Biomark. 2018 Feb 6;21(2):433-438.

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