25-OH Vitamin D3 (Highly Pure)


Catalog Number: B2010607 (5 mg)
25-OH Vitamin D3 is a highly pure monohydroxylated metabolite of vitamin D3. This product has been used as versatile molecular tool in the study of the metabolism of vitamin D as well as the development of vitamin D assays. It has also been used in a wide array of other biochemical and immunological applications. Custom bulk amounts of this product are available upon request.

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SKU: B2010607 Categories: ,


25-OH Vitamin D3
Catalog number: B2010607
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 mg
Molecular Weight or Concentration: 400.64
Supplied as: Powder
Applications: versatile molecular tool in the study of the metabolism of vitamin D as well as the development of Vitamin D assays
Storage: -20C
Keywords: 25-hydroxy vitamin D3, 25-OH-D₃, Vitamin D₃, 25-Hydroxy-vitamin D3
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Tripkovic L, Lambert H, Hart K, Smith CP, Bucca G, Penson S, Chope G,
Hyppönen E, Berry J, Vieth R, Lanham-New S. Comparison of vitamin D2 and vitamin
D3 supplementation in raising serum 25-hydroxyvitamin D status: a systematic
review and meta-analysis. Am J Clin Nutr. 2012 Jun;95(6):1357-64.

2: Shab-Bidar S, Bours S, Geusens PP, Kessels AG, van den Bergh JP. Serum
25(OH)D response to vitamin D3 supplementation: a meta-regression analysis.
Nutrition. 2014 Sep;30(9):975-85.

3: Guo J, Lovegrove JA, Givens DI. 25(OH)D3-enriched or fortified foods are more
efficient at tackling inadequate vitamin D status than vitamin D3. Proc Nutr
Soc. 2018 Aug;77(3):282-291.

4: Zhu H, Wu R, Gu Z, Ji M, Xu Q. Vitamin D3 Is Transformed into 1,25(OH)2D3 by
Triggering CYP3A11(CYP3A4) Activity and Hydrolyzing Midazolam. Med Sci Monit.
2019 Dec 2;25:9159-9166.

5: Wilson LR, Tripkovic L, Hart KH, Lanham-New SA. Vitamin D deficiency as a
public health issue: using vitamin D2 or vitamin D3 in future fortification
strategies. Proc Nutr Soc. 2017 Aug;76(3):392-399.

6: Minisola S, De Martino V, Cipriani C, Pepe J, Colangelo L, Sonato C. Vitamin
D3 and 25(OH)D3: an open debate. Am J Clin Nutr. 2021 Sep 1;114(3):1251. doi:
10.1093/ajcn/nqab254. PMID: 34467972.

7: Hassan AB, Hozayen RF, Alotaibi RA, Tayem YI. Therapeutic and maintenance
regimens of vitamin D3 supplementation in healthy adults: A systematic review.
Cell Mol Biol (Noisy-le-grand). 2018 Nov 30;64(14):8-14.

8: Ali AM, Alobaid A, Malhis TN, Khattab AF. Effect of vitamin D3
supplementation in pregnancy on risk of pre-eclampsia – Randomized controlled
trial. Clin Nutr. 2019 Apr;38(2):557-563.

9: Martineau AR, Thummel KE, Wang Z, Jolliffe DA, Boucher BJ, Griffin SJ,
Forouhi NG, Hitman GA. Differential Effects of Oral Boluses of Vitamin D2 vs
Vitamin D3 on Vitamin D Metabolism: A Randomized Controlled Trial. J Clin
Endocrinol Metab. 2019 Dec 1;104(12):5831-5839.
10: Boland R, Buitrago C, De Boland AR. Modulation of tyrosine phosphorylation
signalling pathways by 1alpha,25(OH)2-vitamin D3. Trends Endocrinol Metab. 2005

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