25-hydroxycholesterol (Highly Pure)

Product Description

25-hydroxycholesterol (Highly Pure)
Catalog number: B2014824
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 2 mg
Molecular Weight or Concentration: N/A
Supplied as: N/A
Applications: molecular tool for various biochemical applications
Storage: N/A
Keywords: 25-hydroxycholesterol
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Odnoshivkina UG, Kuznetsova EA, Petrov AM. 25-Hydroxycholesterol as a Signaling Molecule of the Nervous System Biochemistry (Mosc). 2022 Jun;87(6):524-537.
2: Trindade BC, Ceglia S, Berthelette A, Raso F, Howley K, Muppidi JR, Reboldi A. The cholesterol metabolite 25-hydroxycholesterol restrains the transcriptional regulator SREBP2 and limits intestinal IgA plasma cell differentiation Immunity. 2021 Oct 12;54(10):2273-2287.e6.
3: Zhang J, Zhu Y, Wang X, Wang J. 25-hydroxycholesterol: an integrator of antiviral ability and signaling Front Immunol. 2023 Sep 13;14:1268104.
4: Madenspacher JH, Morrell ED, McDonald JG, Thompson BM, Li Y, Birukov KG, Birukova AA, Stapleton RD, Alejo A, Karmaus PW, Meacham JM, Rai P, Mikacenic C, Wurfel MM, Fessler MB. 25-Hydroxycholesterol exacerbates vascular leak during acute lung injury JCI Insight. 2023 Apr 10;8(7):e155448.
5: Reboldi A, Dang EV, McDonald JG, Liang G, Russell DW, Cyster JG. Inflammation. 25-Hydroxycholesterol suppresses interleukin-1-driven inflammation downstream of type I interferon Science. 2014 Aug 8;345(6197):679-84.
6: Ejam SS, Saleh RO, Catalan Opulencia MJ, Najm MA, Makhmudova A, Jalil AT, Abdelbasset WK, Al-Gazally ME, Hammid AT, Mustafa YF, Sergeevna SE, Karampoor S, Mirzaei R. Pathogenic role of 25-hydroxycholesterol in cancer development and progression Future Oncol. 2022 Dec;18(39):4415-4442.
7: Chen JH, Peng DQ. Is 25-hydroxycholesterol the interplay of statins and inflammation? Int J Cardiol. 2015 Apr 1;184:255-256.
8: Liu SY, Aliyari R, Chikere K, Li G, Marsden MD, Smith JK, Pernet O, Guo H, Nusbaum R, Zack JA, Freiberg AN, Su L, Lee B, Cheng G. Interferon-inducible cholesterol-25-hydroxylase broadly inhibits viral entry by production of 25-hydroxycholesterol Immunity. 2013 Jan 24;38(1):92-105.
9: Piper CJM, Mauri C. 25-hydroxycholesterol: Gatekeeper of intestinal IgA Immunity. 2021 Oct 12;54(10):2182-2185.
10: Domingues MM, Gomes B, Hollmann A, Santos NC. 25-Hydroxycholesterol Effect on Membrane Structure and Mechanical Properties Int J Mol Sci. 2021 Mar 4;22(5):2574.

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