Z-Val-Ala-Asp Fluoromethyl Ketone


Catalog Number: B2013836 (1.5 mg)
Z-Val-Ala-Asp Fluoromethyl Ketone is a high quality Non-methylated competitive and irreversible inhibitor of caspase-1. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

Live enquiry about this product via Text/SMS: 1-858-900-3210.

In stock

SKU: B2013836 Categories: , Tag:


Z-Val-Ala-Asp Fluoromethyl Ketone
Catalog number: B2013836
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1.5 mg
Molecular Weight or Concentration:
453.46 g/mol
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: −20°C
Keywords: Z-VAD-FMK, Non-methylated
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Chu J, Liu CX, Song R, Li QL. Ferrostatin-1 protects HT-22 cells from oxidative toxicity Neural Regen Res. 2020 Mar;15(3):528-536.
2: Atar O, Avraham KB. Anti-apoptotic factor z-Val-Ala-Asp-fluoromethylketone promotes the survival of cochlear hair cells in a mouse model for human deafness Neuroscience. 2010 Jul 14;168(3):851-7.
3: Kugawa F, Ueno A, Aoki M. Apoptosis of NG108-15 cells induced by buprenorphine hydrochloride occurs via the caspase-3 pathway Biol Pharm Bull. 2000 Aug;23(8):930-5.
4: Fei XF, Wang BX, Tashiro S, Li TJ, Ma JS, Ikejima T. Apoptotic effects of ginsenoside Rh2 on human malignant melanoma A375-S2 cells Acta Pharmacol Sin. 2002 Apr;23(4):315-22.
5: Yang HL, Liu HW, Shrestha S, Thiyagarajan V, Huang HC, Hseu YC. Antrodia salmonea induces apoptosis and enhances cytoprotective autophagy in colon cancer cells Aging (Albany NY). 2021 May 24;13(12):15964-15989.
6: Suzuki H, Sozen T, Hasegawa Y, Chen W, Zhang JH. Caspase-1 inhibitor prevents neurogenic pulmonary edema after subarachnoid hemorrhage in mice Stroke. 2009 Dec;40(12):3872-5.
7: Halder SK, Matsunaga H, Ueda H. Neuron-specific non-classical release of prothymosin alpha: a novel neuroprotective damage-associated molecular patterns J Neurochem. 2012 Oct;123(2):262-75.
8: Okuda T, Sugahara K, Takemoto T, Shimogori H, Yamashita H. Inhibition of caspases alleviates gentamicin-induced cochlear damage in guinea pigs Auris Nasus Larynx. 2005 Mar;32(1):33-7.
9: Supinski GS, Callahan LA. Caspase activation contributes to endotoxin-induced diaphragm weakness J Appl Physiol (1985). 2006 Jun;100(6):1770-7.
10: Hughes FM Jr, Evans-Storms RB, Cidlowski JA. Evidence that non-caspase proteases are required for chromatin degradation during apoptosis Cell Death Differ. 1998 Dec;5(12):1017-27.

Products Related to Z-Val-Ala-Asp Fluoromethyl Ketone can be found at Chemicals

Additional information

Weight 48 oz
Dimensions 8 × 8 × 8 in

How to Order

1- Order online using our website’s automated shopping cart and checkout system (available 24/7).

2- Order by email: (we accept electronic PO, available 24/7).

3- Order by Fax: 1-858-437-9884 (available 24/7).

4- Order by phone: 1-858-900-3210 (6 am – 8 pm PST).

5- Order by Text/SMS: 1-858-900-3210 (6 am – 8 pm PST).